Research project: Circulating haemostatic factors and pro-coagulant microparticles in pre-eclampsia
During normal pregnancy a local hypercoagulable state is known to be essential for physiological placental haemostasis. However, small placental thrombi are frequently observed in women with pre-eclampsia (P-EC), and may compromise placental perfusion and fetal growth development, possibly leading to intrauterine death.