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The University of Southampton
Medicine

Professor Myron Christodoulides  BSc, PhD

Professor of Bacteriology

Professor Myron Christodoulides 's photo

Myron Christodoulides is Professor of Bacteriology in the Faculty of Medicine, University of Southampton.

Myron is a Professor of Bacteriology with broad interests in bacterial infections of humans and animals, in vaccine development and the discovery of new antimicrobials. His other main interests include vaccine development for neglected tropical diseases. His research portfolio involves collaborators from within the UK and from countries within the EU, Latin America, North America, Africa including South Africa, and from the Commonwealth - Australia, New Zealand and India.

Myron Christodoulides is a graduate in microbiology from University College London and the University of Glasgow and a specialist in bacteriology. His key interests are broad and encompass the development of vaccines for bacterial infections and for neglected tropical diseases; drug discovery for novel antimicrobials; development of rapid diagnostic assays. Central to his research is multi- and inter-disciplinary collaboration with colleagues all over the world.

Qualifications

BSc, 1st Class, Microbiology, University College London 1983

PhD, Microbiology, University of Glasgow 1987

Appointments held

NERC Visiting Postdoctoral Fellow in Biotechnology, Health & Welfare, Canada, Ottawa 1987.

Postdoctoral Research Fellow, Department of Pathology, University of Newcastle 1988.

Postdoctoral Research Fellow, Molecular Microbiology, University of Southampton 1990.

Postdoctoral Senior Research Fellow, Molecular Microbiology, University of Southampton 1994.

Senior Research Fellow, Molecular Microbiology, University of Southampton 1995.

Senior Lecturer in Molecular Microbiology, University of Southampton 2005-2012.

Reader in Bacteriology, Molecular Microbiology, University of Southampton 2102-2016.

 

Research interests

Current research interests and ongoing projects are in the following areas:

  1. Neisseria gonorrhoeae vaccine development.
  2. Drug discovery for multi-drug/antibiotic resistant bacteria, using natural products and synthetic chemistry.
  3. Vaccine development for Leishmania parasites.
  4. Pathogenesis of Neisseria infections.
  5. Pathogenesis of other bacterial infections, including Streptococcus agalactiae neonatal meningitis; Streptococcus pneumoniae infection; molecular and cellular basis of microbial keratitis caused by Pseudomonas aeruginosa, S. pneumoniae, N. gonorrhoeae and Staphylococcus aureus.
  6. Bacterial mechanisms of invasion of the blood-CSF barrier.
  7. Vaccines for infections of animals, e.g. Brachyspira infection of poultry, Dichelobacter infection of ungulates, Fusobacterium spp. – host cell interactions Identifying commonality between human and animal pathogen vaccine antigens.
  8. Mechanisms of microbial skin infection and wound healing.
  9. Rapid diagnostic assay development for covid-19.
  10. Rapid diagnostic assays based on microfluidic platforms.
  11. Climate change and antimicrobial resistance.

Research group

Clinical and Experimental Sciences

Affiliate research group

Infection and Immunity Research group

Postgraduate supervision (graduates)

Jenny Williams MPhil (2003) PhD (2011)
Mark Fowler, PhD (2004)
Anna Tocheva (2011)
Khalil Alkuwaity (2011)
Claire Heath (2011)
Dr Miao-Chiu Hung (2011)
Dr. Ahmad Elsahn (2017)
Hannia Liliana Almonacid Mendoza (2018)
Daniel Holbrook (2018)
Aiste Dijokaite (2021)
‘Supervisor of the Year’ in the Faculty of Medicine, 2011, for commitment to postgraduate supervision and training.
Number of postdoctoral researchers trained = >30 (UK and overseas).
Number of undergraduate EU and South American research students enrolled in projects >10.

External responsibilities:

  • Chairman of Scientific and Medical Advisory Panel for Meningitis Now (2011-2016).
  • Member of Scientific Advisory Panel for Meningitis UK charity (2011-2016)
  • Member of Technology Strategy Board/MRC expert panel (2012-2018)
  • Member of Science Media Expert.
  • Member of UK Veterinary Vaccine Network.
  • Member of Gonococcal Vaccine Consortium (NIAID-sponsored).
  • Member of BactVacc network (UK-MRC sponsored)
  • Member of VALIDATE (MRC)

Editorial board membership;

  • Antibiotics (Basel) Sept 2019
  • Expert Reviews in Vaccines (Aug 2014-)
  • Advances in Preventative Medicine (2012-2017)

Research grant proposal reviewer: for the Medical Research Council, BBSRC, Technology and Strategy Board, Wellcome Trust, Human Frontier Science Program, World Health Organisation, The Meningitis Trust, Meningitis Research Foundation, Meningitis UK, Hadwen Trust, NIHR, NWO-Netherlands, Israeli Science Foundation, US DoD CDMRP Medical Research Program, ISF Sweden, Sir Charles Gairdner and Osborne Park Health Care Group.

Journal referee: for Science, Science Translational Medicine, Journal of Clinical Investigation (Insight), PLOS Pathogens, PLOS One, Molecular Microbiology, Cellular Microbiology, Infection and Immunity, Journal of Bacteriology, Vaccine, Biochem and Biophy Acta, APMIS, Microbes and Infection, Brain Research, Journal of Leukocyte Biology, Microbiology, Critical Care, Inflammation Research, Adv Prevent Med., Scand J Immunol. Antimicrobial Agents and Chemotherapy, Cytokine, BBRes Comm., International Journal of Antimicrobial Agents, Protein Expression and Purification, Clinical Microbiology Reviews, Rubriq.com., Trends in Molecular Medicine, Microbiology and Immunology (Japan), Acta Tropica, BMC Microbiology, Microbial Cell Factories, J Proteome Res., Medical Science Monitor, Vaccines (Basel), Pathogens (Basel), Revista da Sociedade Brasileira de Medicina Tropical / Journal of the Brazilian Society of Tropical Medicine, Journal of Infection, Expert review of Drug Development, Scientific Reports, Frontiers in Microbiology, Journal of Global Antimicrobial Resistance, Aquaculture, J Poultry Science, Tropical Medicine (Basel).

 

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BM5 Year 1 & 2 Microbiology. Member of undergraduate BM5 course working parties, semester working parties, Year 1 & 2 steering group, intermediate examinations working party. Examination and course assignment marking (Years 1-5 as necessary).

Past teaching responsibilities:

  • Lecturer to postgraduate 4 year PhD program in Infection and Immunity (retired).
  • BM5 Year 2, Semester 3 co-ordinator - responsible for semester administration, exams and assessments, validation and moderation and review (retired).
  • BM5 Year 2, Gastro-intestinal systems course co-ordinator (retired).
  • BM5 Head of Field Microbiology for BMEDSCI/MMEDSCI projects, responsible for project-student matching (retired).
  • Contributor as facilitator on BM4 and IPL courses.
  • Lecturer on MSc programs in microbiology at the University of Surrey and University of Bath.
Professor Myron Christodoulides
Neisseria Research laboratory, Molecular Microbiology, MP814, Sir Henry Wellcome Laboratories, South Academic and Pathology Block, Division of Clinical and Experimental Sciences, University of Southampton Faculty of Medicine, Southampton General Hospital Tremona Road Southampton SO16 6YD. Phone: (023) 8120 8896

Room Number: SGH/LC79/MP814

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