Our research utilises a multidisciplinary approach to explore the mechanisms underlying the interplay between environmental factors, genetic and epigenetic processes and their influence on disease risk across the lifecourse.
Our research aims to understand how epigenetic modifications induced through environmental exposures at different life stages can modulate disease risk throughout the lifecourse. We utilise our access to large cohorts and primary tissues to study both the environmental influences on the genome and the mechanisms underlying disease risk. We employ state-of-the-art cellular, molecular, and bioinformatic approaches to our work, including transcriptomics, single-cell transcriptomics, genome-wide methylation studies and innovative machine learning techniques.
Our main research areas include:
Our aim is to use this knowledge to identify individuals with increased risk profiles, inform nutritional recommendations and develop novel/targeted intervention strategies to promote healthy ageing and reduce the burden of non-communicable diseases (NCDs) throughout life.
