Publications

Read more about the outputs from our research collaborations and our impact.

A 3D-induced pluripotent stem cell-derived human neural culture model to study certain molecular and biochemical aspects of Alzheimer’s disease

Preeti Prasannan,

Elodie Jane Siney,

Shreyasi Chatterjee,

David Johnston,

Mohammad Shah,

Amritpal Mudher,

& Sandrine Willaime-Morawek

, 2022 , In Vitro Models , 1 , pages447–462

DOI: 10.1007/s44164-022-00038-5

Type: article

A systematic review of artificial intelligence and machine learning applications to inflammatory bowel disease, with practical guidelines for interpretation

Imogen, Sian Stafford,

Mark M Gosink,

Enrico Mossotto,

Sarah Ennis,

& Manfred Hauben

, 2022 , Inflammatory Bowel Diseases , 28 (10)

DOI: 10.1093/ibd/izac115

Type: article

Development and validation of population clusters for integrating health and social care

Hajira Dambha-Miller,

Glenn Simpson,

Ralph K Akyea,

Hilda Hounkpatin,

Leanne Morrison,

Jon Gibson,

Jonathan Stokes,

Nazrul Islam,

Adriane Chapman,

Beth Stuart,

Francesco Zaccardi,

Zlatko Zlatev,

Karen Jones,

Paul Roderick,

Michael Boniface,

Miriam Santer,

& Andrew Farmer

, 2022 , JMIR Research Protocols , 11 (6)

DOI: 10.2196/34405

Type: article

From outcome measurement to improving health outcomes following lower limb amputation - A narrative review exploring outcome measurement from a clinical practice perspective

Chantel, Marie Ostler,

Helen Scott,

Imad Sedki,

Sisary Kheng,

Margaret Donovan-Hall,

Alexander Dickinson,

& Cheryl Metcalf

, 2022 , Prosthetics and Orthotics International

DOI: 10.31224/osf.io/kfgdy

Type: article

Deleterious genetic variation across the NOD-signaling pathway is associated with reduced NFKB-signaling transcription and upregulation of alternative inflammatory transcripts in paediatric inflammatory bowel disease

James Ashton,

Konstantinos Boukas,

Imogen, Sian Stafford,

Guo Cheng,

Rachel Haggarty,

Tracy Coelho,

Akshay Batra,

Nadeem A. Afzal,

Anthony Williams,

Marta Polak,

R. Mark Beattie,

& Sarah Ennis

, 2022 , Inflammatory Bowel Diseases , 28 (6) , 912--922

DOI: 10.1093/ibd/izab318

Type: article

Multi-excitation Raman spectroscopy for label-free, strain-level characterization of bacterial pathogens in artificial sputum media

Jeremy Webb,

Adam Lister,

Callum Highmore,

Niall Hanrahan,

James, Arthur Read,

Alasdair, Peter Stuart Munro,

Samuel Tan,

Raymond Allan,

Saul Faust,

& Sumeet Mahajan

, 2022 , Analytical Chemistry , 94 (2) , 669--677

DOI: 10.1021/acs.analchem.1c02501

Type: article

Institute for Life Sciences Annual Report 2022

Peter Smith,

Elizabeth Gilbride,

Alexandra Mant,

& Janette Thompson

, 2022

DOI: 10.5258/SOTON/P1116

Type: report

Extensive substrate recognition by the streptococcal antibody-degrading enzymes IdeS and EndoS

Abigail S L Sudol,

John Butler,

Dylan P Ivory,

Ivo Tews,

& Max Crispin

, 2022 , Nature Communications , 13 (1)

DOI: 10.1038/s41467-022-35340-z

Type: article

Maternal undernutrition induces cell signalling and metabolic dysfunction in undifferentiated mouse embryonic stem cells

Pooja Khurana,

Andrew Lee Cox,

Barira Islam,

Judith Eckert,

Sandrine Willaime-Morawek,

Joanna Mary Gould,

Neil Smyth,

Patrick C McHugh,

& Thomas Fleming

, 2022 , Stem Cells Reviews and Reports

DOI: 10.1007/s12015-022-10490-1

Type: article

Uncovering cryptic pockets in the SARS-CoV-2 spike glycoprotein

Lorena Zuzic,

Firdaus Samsudin,

Aishwary T. Shivgan,

Palur V. Raghuvamsi,

Jan K. Marzinek,

Alister Boags,

Conrado Pedebos,

Nikhil K. Tulsian,

Jim Warwicker,

Paul MacAry,

Max Crispin,

Syma Khalid,

Ganesh S. Anand,

& Peter J. Bond

, 2022 , Structure , 30 (8) , 1062--1074.e4

DOI: 10.1016/j.str.2022.05.006

Type: article