Research project

Clough PG/12/18/29453 Maternal over-nutrition and offspring microvascular function

Lead researchers:

Emeritus Professor Geraldine Clough
Other researchers:

Professor Chris Byrne
Research funder:

British Heart Foundation
Status:

Not active

Staff

Lead researchers

Emeritus Professor Geraldine Clough

Research interests

Early identification of risk of small vessel dysfunction in cardio-metabolic disease
Mechanisms underlying the developmental priming of vascular plasticity and endothelial dysfunction by maternal diet
Development of novel devices and approaches for the multiscale assessment of the dynamics of microvascular perfusion

Connect with Geraldine

Email: G.F.Clough@soton.ac.uk

Other researchers

Professor Chris Byrne

Professor of Endocrinol & Met

Connect with Chris

Email: C.D.Byrne@soton.ac.uk

Research outputs

Soft tissue 3D imaging in the lab through optimised propagation-based phase contrast computed tomography

Berit Zeller-Plumhoff, Joshua L. Mead, Deck Tan, Tiina Roose, Geraldine Clough, Richard Boardman & Philipp Schneider, 2017, Optics Express

DOI: 10.1364/OE.25.033451

Type: article

Investigation of microvascular morphological measures for skeletal muscle tissue oxygenation by image-based modelling in 3D

Berit Zeller-Plumhoff, Keith Daly, Geraldine Clough, Philipp Schneider & Tiina Roose, 2017, Journal of the Royal Society Interface, 14(135)

DOI: 10.1098/rsif.2017.0635

Type: article

Time-dependent behavior of microvascular blood flow and oxygenation

Katarzyna Z. Kuliga, Rodney Gush, Geraldine F. Clough & Andrew J. Chipperfield, 2017, IEEE Transactions on Biomedical Engineering

DOI: 10.1109/TBME.2017.2737328

Type: article

Phase contrast synchrotron radiation computed tomography of muscle spindles in the mouse soleus muscle

Berit Zeller-Plumhoff, Tiina Roose, Mark Mavrogordato, Orestis Katsamenis, Christopher Torrens, Philipp Schneider & Geraldine Clough, 2017, Journal of Anatomy, 230(6), 859-865

DOI: 10.1111/joa.12606

Type: article

Image-based modelling of skeletal muscle oxygenation

Berit Zeller-Plumhoff, Tiina Roose, Geraldine Clough & Philipp Schneider, 2017, Journal of the Royal Society Interface, 14(127)

DOI: 10.1098/rsif.2016.0992

Type: article

An image-based computation of microvascular dysfunction

2017

Type: thesis

Developmental conditioning of endothelium-derived hyperpolarizing factor-mediated vasorelaxation

Rebecca Stead, Moji G Musa, Claire L Bryant, Stuart A Lanham, David A Johnston, Richard Reynolds, Christopher Torrens, Paul A Fraser & Geraldine F Clough, 2016, Journal of Hypertension, 34(3), 452-63; discussion 463

DOI: 10.1097/HJH.0000000000000833

Type: article