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Research project

D Boche: J Amin Fellowship, Systemic and central inflammation in dementia with Lewy Bodies

Staff

Lead researcher

Professor Delphine Boche

Professor of Neuroimmunopathology

Research interests

  • Delphine serves on a range of neuroscience research projects focusing on neuroinflammation and neurodegeneration.
  • Her main research interest is to develop a greater understanding of the role of neuroinflammation in relation with ageing, neurological diseases and systemic inflammation, using the approaches of human brain analysis. Her research focuses on microglia, the immune cells of the brain, where she has developed protocols to immunophenotype microglia in humans using markers relating to a specific function allowing us to investigate the role of these cells in different neurological conditions.
  • Her work is located at the junction between clinical neurodegenerative disease, human neuropathology and experimental neuroscience where she has developed an expertise in neuroimmunopathology

Connect with Delphine

Other researchers

Emeritus Professor Clive Holmes

Connect with Clive

Research outputs

Neuroinflammation in dementia with Lewy bodies: a human post-mortem study
Jay Amin,
Clive Holmes,
Robert B. Dorey,
Emmanuele Tommasino,
Yuri Reis Casal,
Daisy Williams,
Charles Dupuy,
James Nicoll,
& Delphine Boche
, 2020 , Translational Psychiatry , 10 (1) , 1--11
DOI: 10.1038/s41398-020-00954-8
Type: article
Peripheral immunophenotype in Dementia with Lewy bodies and Alzheimer’s disease: an observational clinical study
Jay Amin,
Delphine Boche,
Zoe Clough,
Jessica Teeling,
Anthony Williams,
Yifang Gao,
Lindsey Chudley,
Laurie Lau,
Florence Smith,
Scott Harris,
& Clive Holmes
, 2020 , Journal of Neurology, Neurosurgery, and Psychiatry , 91 (11) , 1219--1226
DOI: 10.1136/jnnp-2020-323603
Type: article
What do we know about the inflammasome in humans?
Jay Amin,
Delphine Boche,
& Sonja Rakic
, 2017 , Brain Pathology , 27 (2) , 192--204
DOI: 10.1111/bpa.12479
Type: article
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