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Doctor Jay Amin

Doctor Jay Amin

 BM, MRCPsych, PhD
Assoc Prof in Psychiatry of Older Age

Research interests

  • Examining the profile of neuroinflammation in Dementia with Lewy bodies
  • Permeability of the blood-brain barrier in Alzheimer’s disease (PEBBAL) measured using dynamic contrast-enhanced MRI
  • Diagnostic biomarkers of gut microbiome-associated phenotypes predictive of healthy aging and neurodegenerative disease (BIO-AGE)

More research

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Research

Research groups

Research interests

  • Examining the profile of neuroinflammation in Dementia with Lewy bodies
  • Permeability of the blood-brain barrier in Alzheimer’s disease (PEBBAL) measured using dynamic contrast-enhanced MRI
  • Diagnostic biomarkers of gut microbiome-associated phenotypes predictive of healthy aging and neurodegenerative disease (BIO-AGE)
  • Use of electronic patient records to explore clinical features and outcomes in Dementia with Lewy bodies

Current research

Dr Amin’s research interests focus on the role of inflammation in Dementia with Lewy bodies, Alzheimer’s disease and other neurodegenerative conditions. This includes exploration of the role of cerebral inflammatory markers in post-mortem brain tissue, and peripheral inflammatory markers using techniques such as multiplex immunoassay and flow cytometry.

 

 

Clinically, Dr Amin’s interests are in improving quality of life and outcomes in people living with dementia, and their carers.

Dr Amin is also principal investigator for several commercial and non-commercial clinical trials at the Memory Assessment and Research Centre in Southampton. These include drug trials testing novel agents in Alzheimer’s disease, Dementia with Lewy bodies and Mild Cognitive Impairment

Research projects

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