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Research project

Dr Jane Cleal: Functional gene mapping of the endometrial phenotype involved in successful pregnancy: combining 3D imaging and single cell transcriptomics

Staff

Lead researcher

Dr Jane Cleal PhD

Associate Professor

Research interests

  • Areas of Scientific Expertise:
  • Reproductive Cell Biology – Fundamental mechanisms of cell biology in placenta and endometrium and the impact on the intra-uterine environment, fetal development and lifelong health.Regulation of Reproductive Cell Biology – Maternal exposures and molecular regulation of cellular gene expression, phenotype and function in placenta and endometrium and the clinical translation.Disease/phenotype – Fetal growth, Obesity, Cardiometabolic programming, Subfertility, Recurrent pregnancy loss.Cellular mechanisms – Membrane transport, endocytosis, vesicular transport & signalling, gene transcription, microRNA biology, epigenetic regulation.Vitamin D - Transport, regulation, metabolism and signalling.
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Other researchers

Professor Rohan Lewis PhD, FTPS

Prof of Placental&Integrative Physiology
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Professor Ying Cheong

Professor of Reproductive Medicine
Connect with Ying

Research outputs

Rebecca Davies, Catherine Griffiths, Kathryn Askelund, Eleni Palaiologou, Jane K. Cleal, Anton Page, David S. Chatelet, Patricia Goggin, Larry Chamley & Rohan M. Lewis, 2022, Placenta, 123, 24-30
Type: article
Brogan Ashley, Claire Simner, Antigoni Manousopoulou, Carl Jenkinson, Felicity Hey, Jennifer M. Frost, Faisal I Rezwan, Cory H White, Emma Lofthouse, Emily Hyde, Laura, Diana Frances Cooke, Sheila Barton, Pamela A Mahon, Elizabeth Curtis, Rebecca Moon, Sarah Crozier, Hazel Inskip, Keith Godfrey, John Holloway, Cyrus Cooper, Kerry S. Jones, Rohan Lewis, Martin Hewison, Spiros Garbis, Miguel R. Branco, Nicholas Harvey & Jane Cleal, 2022, eLife, 11
Type: article
Rohan Lewis, Jane Cleal & Bram Sengers, 2020, Placenta, 93, 43-48
Type: review