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Research project

Growth and development of bacterial 3-dimensional structures - A multidisciplinary approach.

  • Lead researcher:
  • Research funder:
    Biotechnology & Biological Sciences Research Council
  • Status:
    Not active

Project overview

David Phillips Fellowship Award.
The objective of this research is to integrate approaches to the study of autonomously replicating cells in confined environments (here we consider malignancies and surface-attached bacteria). It is proposed that the evolutionary and ecological pressures for growth in these taxonomically very different systems are fundamentally the same, and thus can be addressed within the same experimental and conceptual framework. Processes of interest in tumorigenesis include i) destabilisation if the cancer cell genome, ii) viral-host cell interactions (in certain cancers) and iii) differentiation and death of cancer cells inside tumours. This project will integrate approaches to bacterial and tumour development by studying these processes in 3-dimensional structures in bacterial biofilms.

Staff

Lead researcher

Professor Jeremy Webb

Professor of Microbiology

Connect with Jeremy

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