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Research project

Dr Vince O'Connor MRC TSE Highlight

Staff

Lead researcher

Professor Vincent O'connor

Professor of Neurochemistry

Research interests

  • Molecular mechanism of synaptic function and dysfunction
  • Synaptic degeneration
  • Genetic models of synaptic and neuronal dysfunction

Research outputs

Alpha-synuclein deficiency in the C57BL/6JOlaHsd strain does not modify disease progression in the ME7-model of prion disease
A.A. Asuni,
K. Hilton,
Z. Siskova,
K. Lunnon,
R. Reynolds,
V.H. Perry,
& V. O'Connor
, 2010 , Neuroscience , 165 (3) , 662--674
DOI: 10.1016/j.neuroscience.2009.10.047
Type: article
The role of microglia in synaptic stripping and synaptic degeneration: a revised perspective
V. Hugh Perry,
& Vincent O'Connor
, 2010 , ASN Neuro , 2 (5) , e00047--[11pp]
DOI: 10.1042/AN20100024
Type: article
Reactive hypertrophy of synaptic varicosities within the hippocampus of prion-infected mice
Zuzana Sisková,
Nik K Sanyal,
Adam Orban,
Vincent O'Connor,
& V Hugh Perry
, 2010 , Biochemical Society Transactions , 38 (2) , 471--475
DOI: 10.1042/BST0380471
Type: article
Degenerating synaptic boutons in prion disease. Microglia activation without synaptic stripping
Zuzana Siskova,
Anton Page,
Vincent O'Connor,
& Victor Hugh Perry
, 2009 , The American Journal of Pathology , 175 (4) , 1610--1621
DOI: 10.2353/ajpath.2009.090372
Type: article
Selective presynaptic degeneration in the synaptopathy associated with ME7-induced hippocampal pathology
B.C. Gray,
Z. Siskova,
V.H. Perry,
& V. O'Connor
, 2009 , Neurobiology of Disease , 35 (1) , 63--74
DOI: 10.1016/j.nbd.2009.04.001
Type: article