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Research project

TISuMR: Integrated Tissue Slice Culture and NMR Metabolomics – A Novel Approach Towards Systemic

  • Research groups:
  • Lead researcher:
  • Research funder:
    European Union
  • Status:
    Not active

Project overview

This international collaboration, led by Southampton, aims to provide a radically new technological platform for the integrated culture and NMR observation of liver tissue slices, with the immediate objective to elucidate the mechanism of liver damage by cholestasis.


Lead researcher

Professor Marcel Utz

Professorial Fellow-Research

Research interests

  • Integration of microfluidic lab-on-a-chip technology with NMR spectroscopy and imaging;
  • Behaviour of complex materials.

Collaborating research institutes, centres and groups

Research outputs

Marek Plata,
Manvendra Sharma,
, 2022 , Journal of the American Chemical Society , 145 (5) , 3204–3210
Type: article
James Eills,
William G Hale,
, 2021 , Progress in Nuclear Magnetic Resonance Spectroscopy
Type: review
Yibin Sun,
Hongxun Fang,
Xujing Lin,
Xiuxiu Wang,
Ganyu Chen,
Xinchang Wang,
Zhongqun Tian,
Liulin Yang,
& Xiaoyu Cao
, 2021 , Chemistry , 2021 (3) , 948–956
Type: article
Marek Plata,
William G Hale,
Manvendra Sharma,
, 2021 , Lab on a Chip , 21 (8) , 1598--1603
Type: article
Bishnubrata Patra,
Manvendra Sharma,
William G Hale,
, 2021 , Scientific Reports , 11 (1)
Type: article
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