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Research project

Mechanisms of long-range retrograde signal propogation - Deinhardt - BBSRC

Staff

Lead researcher

Professor Katrin Deinhardt

Professor

Research interests

  • Short- and long-range neurotrophin signalling and its role in morphological plasticity
  • Early neuronal dysfunction in disturbed proteostasis
  • Cellular mechanisms that underlie tau propagation across neurons

Collaborating research institutes, centres and groups

Neuroscience

We work on national and global priorities of health and well-being, underpinning research in neuroscience, and age-related neurodegenerative diseases, including Alzheimer’s.

Research outputs

Quantitative and correlative extreme ultraviolet coherent imaging of mouse hippocampal neurons at high resolution
Peter Baksh,
Michal Odstrčil,
Magdalena Miszczak,
Charles Pooley,
Richard Chapman,
Adam Wyatt,
Emma Springate,
John Chad,
Katrin Deinhardt,
Jeremy G. Frey,
& William Brocklesby
, 2020 , Science Advances , 6 (18)
DOI: 10.1126/sciadv.aaz3025
Type: article
A 5′ UTR GGN repeat controls localisation and translation of a potassium leak channel mRNA through G-quadruplex formation
Connor Maltby,
James Schofield,
Steven Houghton,
Ita O'Kelly,
Mariana Vargas-Caballero,
Katrin Deinhardt,
& Mark Coldwell
, 2020 , Nucleic Acids Research , 48 (17) , 9822--9839
DOI: 10.1093/nar/gkaa699
Type: article
Co-culture of murine neurons using a microfluidic device for the study of Tau misfolding propagation
Grace Hallinan,
Dianne Lopez,
Mariana Vargas-caballero,
Jonathan West,
& Katrin Deinhardt
, 2020 , Bio-protocol , 10 (16)
DOI: 10.21769/BioProtoc.3718
Type: article
A primate-specific short GluN2A-NMDA receptor isoform is expressed in the human brain
Mariana Vargas-Caballero,
Hannah, Kate Warming,
Chrysia-Maria Pegasiou,
Aleksandra, Paulina Pitera,
Hanna Kariis,
Steven Houghton,
Ksenia Kurbatskaya,
Aminul Ahmed,
Paul Grundy,
Girish V. Vajramani,
Diederik Bulters,
Xavier Altafaj,
& Katrin Deinhardt
, 2019 , Molecular Brain , 12 (1) , 1--8
DOI: 10.1186/s13041-019-0485-9
Type: article
Proteomic approaches to dissect neuronal signalling pathways
Heather Bowling,
Shruti Nayak,
& Katrin Deinhardt
, 2019
DOI: 10.1007/978-3-030-15950-4_27
Type: bookChapter
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