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Research project

Structural plasticity in antigen selection - Werner - BBSRC

  • Lead researcher:
    Dr Joern Werner
  • Research funder:
    Biotechnology & Biological Sciences Research Council
  • Status:
    Not active

Staff

Lead researcher

Dr Joern Werner

Reader in Structural Biology

Research outputs

Kinetics of abacavir-induced remodelling of the major histocompatibility complex class I peptide repertoire
Patricia Illing,
Andy van Hateren,
Rachel Darley,
Nathan Croft,
Nicole Mifsud,
Samuel King,
Lyudmila Kostenko,
Mandvi Bharadwaj,
James McCluskey,
Timothy Elliott,
& Anthony Purcell
, 2021 , Frontiers in Immunology , 12
DOI: 10.3389/fimmu.2021.672737
Type: article
Protein plasticity and peptide editing in the MHC I antigen processing pathway
Tim Elliott,
& Andrew Van Hateren
, 2018 , Biochemistry , 57 (9) , 1423–1425
DOI: 10.1021/acs.biochem.7b01307
Type: review
The partial dissociation of MHC class I bound peptides exposes their N terminus to trimming by endoplasmic reticulum aminopeptidase 1: ERAP1 trimming of MHC I-bound peptides
Athanasios Papakyriakou,
Emma Reeves,
Mary Beton,
Halina Mikolajek,
Leon Douglas,
Grace Cooper,
Timothy Elliott,
Jorn M. Werner,
& Edward James
, 2018 , The Journal of Biological Chemistry , 293 (20) , 7538--7548
DOI: 10.1074/jbc.RA117.000313
Type: article
Direct evidence for conformational dynamics in major histocompatibility complex class I molecules
Andy van Hateren,
Malcolm Anderson,
Alistair Bailey,
Jörn M Werner,
Paul Skipp,
& Tim Elliott
, 2017 , The Journal of Biological Chemistry , 292 (49) , 20255--20269
DOI: 10.1074/jbc.M117.809624
Type: article
Selector function of MHC I molecules is determined by protein plasticity
Alistair Bailey,
Neil Dalchau,
Rachel Carter,
Stephen Emmott,
Andrew Phillips,
Jorn M. Werner,
& Tim Elliott
, 2015 , Scientific Reports , 5 , 1--15
DOI: 10.1038/srep14928
Type: article
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