Research interests
Key Research Focus and Achievements
Development of cell and tissue engineered-based model systems to examine cell performance when subjected to a range of mechanical and biochemical environments. This involves the elucidation of critical mechano-transduction signaling pathways
Establishment of in vivo models to examine real-time damage in cell and tissues subjected to a range of loading regimens. By using a combined experimental and computational approach, the relative influence of deformation, ischaemia and reperfusion on damage can be examined.
Developing methodologies which enable the collection of biomarkers from the skin, blood and urine from animal and human subjects.
Design of support products which can customise the requirements of patients and minimise their risk of developing pressure ulcers.
Biomechanics of soft tissues in health and disease at different hierarchical levels.
Affiliated Research Group - Continence and Skin Health Technologies
May 2007 - “Multiscale Mechanobiology for Tissue Engineering” Co-Investigator with Lee and Knight UK
EPSRC Platform Grant Scheme.
Oct 2007 - Alternating Low pressure sensor and Airflow”Sole Principal Investigator HillRom France.
May 2010 - “TRANslating Science into Clinically Relevant Information for Pressure-ulcer Therapies and Risk-assessment (TranSCRIPTaR) Network” Co-Applicant with Nixon (PI, Leeds) Oomens, Gefen plus other Institutions in US, Australia, UK and Belgium. World University Network.
June 2010 - “Multi-purpose whole body motion capture” Co-Applicant of successful with Centre for Sports and Exercise Medicine (PI Morrissey) KTA award with Charnwood Dynmaics Ltd.
March 2010 - “AusCAN risk assessment for sitting acquired Pressure Ulcers” Co-Applicant with Stacey (PI, University of Western Australia) and six other Co-Is from Australia, Canada and USA. Australian National Health Medical Research Council.
Nov 2010 - “Complex mechanical loading of cell-seeded constructs can lead to functional repair of cartilage defects” Principal Applicant (Bader) Co-Applicant (Shelton) Furlong Project Grant
Oct 2010 - Beneficial effects of CNP in engineered human cartilage” Co-Applicant with Chowdhury (PI), Ramachandran (both QMUL) and Dr Salter (Edinburgh University) AO Foundation Research Fund.
Membership of Advisory Groups/Government Boards
2011 - Journal of Tissue Viability - Editor
1993 - Member of Editorial Board
2004 - Physiotherapy Journal - International Advisory Board
1999 - Biomedical Materials and Engineering - Member of Editorial Board
2010 - Elected Trustee of European Pressure Ulcer Advisory Panel
2006 - Elected Member of World Council of Biomechanics
2002 - International Federation for Medical and Biological Engineering (IFMBE) Member of Special Interest Group in cellular Engineering
2003 - Institute of Physics and Engineering in Medicine (formerly BES):
2010 - Member of Membership Panel
Academic
- 1990 - Queen Mary University of London (Lee, Knight, Chowdhury)
- 2005 - Various UK Universities including Leeds, Edinburgh etc.
- 2000 - Eindhoven University of Technology, the Netherlands (Oomens,
Baiijens)
- 2008 - University of Western Australia, Australia (Swaine, Stacey)
- 2005 - Tel Aviv University, Israel (Gefen)
- 1999 - Tohoku University, Japan (Sato)
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Industrial
- 2010 - Molnlycke (pressure relieving products)
- 2008 - HillRom (Active support surfaces)
Research group
Fundamental Care and Safety
Research project(s)
This is part of the STAR programme: Development, Implementation & Integration of a Comprehensive Prostate Cancer Survivorship Programme into Practice (The STAR Programme: Personalised Supported Self-Management and Remote Monitoring for Men with Prostate Cancer).
