About
Ivo Tews uses crystallography to study molecular interactions. Particular intrests are in large dynamic macromolecular complexes and time resolved techniques that are applied in immunology, developing novel cancer therapies, and in enzymology.
As chair of the CCP4 project he is involved in software development and use of AI for modern crystallography. He is engaged in then national Digital Reserach Infrastructure (DRI), charinig integrated computing for molecular biology in DRI-IMB, and in synchrotron science at the Diamond Light Source and the European Synchtrotron Radiation Facilty.
Research
Research groups
Research interests
- Cancer immunology, where a structure based approach to rational drug development is applied for novel cancer therapies.
- Natural products biosynthesis to study vitamin B6 biosynthesis by the large PLP syntase complex.
- Bacterial biofilms: understanding of RedOx regulated phosphodiesterase activity in dispersal of biofilms to address chronic infections.
Research projects
Active projects
Researchers:
Researchers:
Sponsor: Cancer Research UK
Completed projects
Researchers:
Researchers:
Sponsor: Science And Technology Facilities Council
Sponsor: Medical Research Council
Researchers:
Researchers:
Sponsor: Cancer Research UK
Researchers:
Sponsor: Wessex Medical Research
Publications
81 publications
Page 7 of 9
Teresa B Fitzpatrick, Nikolaus Amrhein, Barbara Kappes, Peter Macheroux, Ivo Tews & Thomas Raschle,
2007, Biochemical Journal, 407(1), 1-13
DOI: 10.1042/BJ20070765
Type: article
Felix Findeisen, Jürgen U Linder, Anita Schultz, Joachim E Schultz, Britta Brügger, Felix Wieland, Irmgard Sinning & Ivo Tews,
2007, Journal of Molecular Biology, 369(5), 1282-1295
Type: article
Marina Tambasco-Studart, Ivo Tews, Nikolaus Amrhein & Teresa B Fitzpatrick,
2007, Plant Physiology, 144(2), 915-925
Type: article
Martina Neuwirth, Karlheinz Flicker, Marco Strohmeier, Ivo Tews & Peter Macheroux,
2007, Biochemistry, 46(17), 5131-5139
Type: article
Marco Strohmeier, Thomas Raschle, Jacek Mazurkiewicz, Karsten Rippe, Irmgard Sinning, Teresa B Fitzpatrick & Ivo Tews,
2006, Proceedings of the National Academy of Sciences of the United States of America, 103(51), 19284-19289
Type: article
Amira Abdel Motaal, Ivo Tews, Joachim E Schultz & Jürgen U Linder,
2006, Febs Journal, 273(18), 4219-4228
Type: article
Soumya Qbadou, Thomas Becker, Oliver Mirus, Ivo Tews, Jürgen Soll & Enrico Schleiff,
2006, The EMBO Journal, 25(9), 1836-1847
Type: article
Martin Gengenbacher, Teresa B Fitzpatrick, Thomas Raschle, Karlheinz Flicker, Irmgard Sinning, Sylke Müller, Peter Macheroux, Ivo Tews & Barbara Kappes,
2006, The Journal of Biological Chemistry, 281(6), 3633-3641
Type: article
Joachim E. Schultz, Ivo Tews & Jürgen U. Linder,
2006, BIOspektrum, 12(3), 263-265
Type: review
Claudia Seelenmeyer, Sabine Wegehingel, Ivo Tews, Markus Künzler, Markus Aebi & Walter Nickel,
2005, PLoS ONE, 171(2), 373-381
Type: article
Biography
Prizes
- David Blow Prize (2011)
- PD, venia legendi (2011)
- David Blow Prize (2011)
- PD, venia legendi (2011)