About
Ivo Tews uses crystallography to study molecular interactions. Particular intrests are in large dynamic macromolecular complexes and time resolved techniques. As a member of the CCP4 project for crystallographic software he chairs working group 2, and is engaged in Synchrotron Science at the Diamond Light Source and the EUropean Synchtrotron Radiation Facilty.
Research
Research groups
Research interests
- Natural products biosynthesis: a complex cascade of catalytic steps in vitamin B6 biosynthesis is characterised by structures or reaction intermediates in the large PLP syntase complexEdit
- Bacterial biofilms: understanding of RedOx regulated phosphodiesterase activity in dispersal of biofilms to address chronic infections
- Cancer immunology: together with Cancer Immunology at Southampton we use a structure based apporach in developing novel cancer therapie
Research projects
Active projects
Researchers:
Sponsor: Medical Research Council
Researchers:
Sponsor: Cancer Research UK
Completed projects
Researchers:
Researchers:
Sponsor: Science And Technology Facilities Council
Researchers:
Researchers:
Sponsor: Cancer Research UK
Researchers:
Sponsor: Wessex Medical Research
Publications
77 publications
Page 8 of 8
S. Sato, I. Tews & R. J.M. Wilson,
2000, International Journal for Parasitology, 30(4), 427-439
Type: article
Ivo Tews, Anke C. Terwisscha Van Scheltinga, Anastassis Perrakis, Keith S. Wilson & Bauke W. Dijkstra,
1997, Journal of the American Chemical Society, 119(34), 7954-7959
DOI: 10.1021/ja970674i
Type: article
C. E. Vorgias, A. Perrakis & I. Tews,
1996, Annals of the New York Academy of Sciences, 799, 190-192
Type: article
Ivo Tews, A. Perrakis, A. Oppenheim, Z. Dauter, K. S. Wilson & C. E. Vorgias,
1996, Nature Structural Biology, 3(7), 638-648
Type: article
Ivo Tews, Renauld Vincentelli & Constantin E. Vorgias,
1996, Gene, 170(1), 63-67
Type: article
A Perrakis, I Tews, Z Dauter, A B Oppenheim, I Chet, K S Wilson & C E Vorgias,
1994, Structure, 2(12), 1169-1180
Type: article
Ivo Tews, Zbigniew Dauter, Amos B. Oppenheim & Constantin E. Vorgias,
1992, Journal of Molecular Biology, 228(2), 696-697
Type: article
Biography
Prizes
- David Blow Prize (2011)
- PD, venia legendi (2011)
- David Blow Prize (2011)
- PD, venia legendi (2011)