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Doctor Angus Wann

Dr Angus Wann

 PhD
Associate Professor in Cell Physiology

Research interests

  • A core interest in the group is molecular, cellular, tissue and organ level mechanobiology. This is often studied through the lens of primary cilia biology. We are developing developmental engineering approaches to tissue biology which also help us to study the relevance of our discovery science in the realms of chondropathies e.g Osteoarthritis and chondrodysplasia.  We have interests in matrix turnover in development and disease and maturation of matrices to support life-long health of tissues.  Finally, we have a long-standing interest in the Intergration of mechanobiology and inflammation through the genes and proteins associated with primary cilia or ciliome. 

More research

Accepting applications from PhD students.

Email: a.k.t.wann@soton.ac.uk

Address: B85, East Highfield Campus, University Road, SO17 1BJ (View in Google Maps)

About

I am a cell biologist and physiologist with an interest in how cells and tissues make the decisions that support homeostasis, phenotypic changes and adaptation in health and disease. I have interests in the primary cilium and how mechanical forces are integrated into cell and tissue signalling programs particularly in the musculoskeletal system. As such the group is active in areas of fundmental discovery science but also disease areas such as chondrodysplasia and osteoarthritis.  

The lab uses a range of techniques including cell and molecular biology, multiscale imaging, the development of developmentally-inspired tissue engineering approaches, single cell and bulk RNA sequencing and in vivo models of development and disease.  

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