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Research project

Cragg CRUK Understanding and Overcoming resistance to antibody therapy

Staff

Lead researcher

Professor Mark Cragg

Professor in Experimental Cancer Biology

Research interests

  • Antibody biology
  • Antibody engineering

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Other researchers

Professor Stephen Beers

Professor of Immunology & Immunotherapy

Research interests

  • Edit
  • Antibody Effector Functions Monoclonal antibodies (mAb) have become established in the treatment of a variety of malignancies - transforming patient outcomes. Despite this undoubted impact, responses remain variable and their mechanisms of action and of tumour resistance are controversial. Our research is focussed on understanding these complex processes using a variety of complementary models and systems to better inform antibody selection, design and clinical application.

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Professor Jon Strefford PhD

Head of School

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Doctor Yury Bogdanov

Lecturer in Transgenic Technologies

Research interests

  • Tumour microenvironment
  • Neurotransmitters in Cancer

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Doctor Stephen Thirdborough

Senior Research Fellow

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Collaborating research institutes, centres and groups

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