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Research project

Dr Tilman Sanchez-Elsner: MicroRNAs and their epigenetic regulation as key factors in airway macrophage dysfunction in asthma

Staff

Lead researcher

Professor Tilman Sanchez-Elsner

Professor of Molecular Medicine

Research outputs

Small RNA species and microRNA profiles are altered in severe asthma nanovesicles from broncho alveolar lavage and associate with impaired lung function and inflammation
Ana Soraia Francisco Garcia,
Eva Garrido Martin,
Hitasha Rupani,
Laurie Lau,
Rocio T Martinez-nunez,
Peter Howarth,
& Tilman Sanchez-Elsner
, 2019 , Noncoding RNA , 54 (1)
DOI: 10.3390/ncrna5040051
Type: article
MicroRNA-31 and MicroRNA-155 are overexpressed in ulcerative colitis and regulate IL-13 signaling by targeting interleukin 13 receptor -1
Markus Gwiggner,
Rocio T. Martinez-Nunez,
Simon R. Whiteoak,
Victor P. Bondanese,
Andrew Claridge,
Jane E. Collins,
J.R. Fraser Cummings,
& Tilman Sanchez-Elsner
, 2018 , Genes , 9 (2)
DOI: 10.3390/genes9020085
Type: article
Genome-wide posttranscriptional dysregulation by microRNAs in human asthma as revealed by Frac-seq.
Rocio, Teresa Martinez-Nunez,
Hitasha Rupani,
Manuela Platé,
Mahesan Niranjan,
Rachel C. Chambers,
Peter H. Howarth,
& Tilman Sanchez-Elsner
, 2018 , The Journal of Immunology , 201 (1) , 251--263
DOI: 10.4049/jimmunol.1701798
Type: article
Modulation of nonsense mediated decay by rapamycin
Rocio Martinez-Nunez,
Andrew Wallace,
Doyle Coyne,
Linnea Jansson,
Miles Rush,
Hanane Ennajdaoui,
Sol Katzman,
Joanne Louise Bailey,
Katrin Deinhardt,
Tilman Sanchez-Elsner,
& Jeremy R. Sanford
, 2017 , Nucleic Acids Research , 45 (6) , 3448--3459
DOI: 10.1093/nar/gkw1109
Type: article
Toll-like receptor 7 is reduced in severe asthma and linked to altered microRNA profile
Hitasha Rupani,
Rocio Teresa Martinez-Nunez,
Patrick Dennison,
Laurie Lau,
Nivenka Jayasekera,
Tom Havelock,
Ana Francisco-Garcia,
Chris Grainge,
Peter Howarth,
& Tilman Sanchez-Elsner
, 2016 , American Journal of Respiratory and Critical Care Medicine , 194 (1) , 26--37
DOI: 10.1164/rccm.201502-0280OC
Type: article
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