Research project

Dr Tilman Sanchez-Elsner: MicroRNAs and their epigenetic regulation as key factors in airway macrophage dysfunction in asthma

Research funder:

Medical Research Council
Status:

Not active

Research outputs

Small RNA species and microRNA profiles are altered in severe asthma nanovesicles from broncho alveolar lavage and associate with impaired lung function and inflammation

2019, Noncoding RNA, 54(1)

DOI: 10.3390/ncrna5040051

Type: article

Genome-wide posttranscriptional dysregulation by microRNAs in human asthma as revealed by Frac-seq.

Rocio, Teresa Martinez-Nunez, Hitasha Rupani, Manuela Platé, Mahesan Niranjan, Rachel C. Chambers, Peter H. Howarth & Tilman Sanchez-Elsner, 2018, The Journal of Immunology, 201(1), 251-263

DOI: 10.4049/jimmunol.1701798

Type: article

MicroRNA-31 and MicroRNA-155 are overexpressed in ulcerative colitis and regulate IL-13 signaling by targeting interleukin 13 receptor -1

2018, Genes, 9(2)

DOI: 10.3390/genes9020085

Type: article

Modulation of nonsense mediated decay by rapamycin

2017, Nucleic Acids Research, 45(6), 3448-3459

DOI: 10.1093/nar/gkw1109

Type: article

Toll-like receptor 7 is reduced in severe asthma and linked to altered microRNA profile

2016, American Journal of Respiratory and Critical Care Medicine, 194(1), 26-37

DOI: 10.1164/rccm.201502-0280OC

Type: article

Identification of host miRNAs that may limit human rhinovirus replication

Victor Paky Bondanese, Ana Francisco-Garcia, Nicole Bedke, Donna E Davies & Tilman Sanchez-Elsner, 2014, World Journal of Biological Chemistry, 5(4), 437-456

DOI: 10.4331/wjbc.v5.i4.437

Type: article

A microRNA network dysregulated in asthma controls IL-6 production in bronchial epithelial cells

Rocio T. Martinez-Nunez, Victor P. Bondanese, Fethi Louafi, Ana S. Francisco-Garcia, Hitasha Rupani, Nicole Bedke, Stephen Holgate, Peter H. Howarth, Donna E. Davies & Tilman Sanchez-Elsner, 2014, PLoS ONE, 9(10), e111659

DOI: 10.1371/journal.pone.0111659

Type: article