This project investigates why some TB lesions progress while some regress by utilising single cell sequencing analysis of our 3D cell culture model of infection, along with engineered real-time readouts. Parallel analysis of clinical samples aims to identify new therapeutic targets.
Collaborating research institutes, centres and groups
Adrie J. C. Steyn,
& Alasdair Leslie, 2022 , Communications Biology , 5 (1317)