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Research project

R Lewis BBSRC Amino acid transport through the placenta BB/I011315/1

Lead researcher:
Other researchers:
Research funder:
Biotechnology & Biological Sciences Research Council
Status:
Not active

Project overview

This interdisciplinary project investigated how amino acids cross the placenta to feed the fetus while it is growing in the womb. We combined laboratory experiments with mathematical modelling to provide new insight into how the placentas work and how membrane transporters carry amino acids across membranes. A key outcome of this work was the demonstration that simply increasing the levels of amino acids in the mothers blood will not effectively increase supply to the fetus.

Staff

Lead researcher

Professor Rohan Lewis PhD, FTPS

Prof of Placental&Integrative Physiolgy

Connect with Rohan

Other researchers

Doctor Bram Sengers

Associate Professor

Connect with Bram

Research outputs

N. Panitchob,
K.L. Widdows,
I.P. Crocker,
E.D. Johnstone,
C.P. Please,
C.P. Sibley,
J.D. Glazier,
R. Lewis,
, 2016 , Biochimica et Biophysica Acta (BBA) - Biomembranes , 1--31
Type: article
N. Pantichob,
K.L. Widdows,
I.P. Crocker,
Mark A. Hanson,
E.D. Johnstone,
C.P. Please,
C.P. Sibley,
J.D. Glazier,
R.M. Lewis,
, 2015 , Journal of Theoretical Biology , 365 , 352--364
Type: article
S. Perazzolo,
B. Hirschmugl,
C. Wadsack,
G. Desoye,
R Lewis,
, 2015
Type: conference
Kate L. Widdows,
Nuttanont Panitchob,
Ian P. Crocker,
C.P. Please,
Mark A. Hanson,
Colin P. Sibley,
Edward D. Johnstone,
Rohan M. Lewis,
& Jocelyn D. Glazier
, 2015 , The FASEB Journal , 29 , 2583--2594
Type: article
E.M. Lofthouse,
S. Perazzolo,
S. Brooks,
I.P. Crocker,
J.D. Glazier,
E.D. Johnstone,
N. Panitchob,
C.P. Sibley,
K.L. Widdows,
& R.M. Lewis
, 2015 , American Journal of Physiology: Regulatory, Integrative and Comparative Physiology , 1--28
Type: article
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