Postgraduate research project

Photoswitchable ion transporters towards supramolecular chemotherapy

Funding
Fully funded (UK only)
Type of degree
Doctor of Philosophy
Entry requirements
2:1 honours degree View full entry requirements
Faculty graduate school
Faculty of Engineering and Physical Sciences
Closing date

About the project

Photoswitches enable remote control of molecular function with high spatiotemporal precision. This interdisciplinary project will involve the synthesis and testing of new drug-like switchable anionophores for use in the controlled treatment of diseases such as cancer.

Compounds which can facilitate ion transport across cell membranes have wide ranging utility across several disease states including cancer and bacterial infection. Our group is particularly interested in developing such bioactive molecules which can be controlled by light, offering improved targeting of cellular and subcellular membranes. These results will guide the development of next generation therapeutics, bridging the gap between supramolecular chemistry and biomedicine. 

Within this project the successful candidate will synthesise and characterise a library of compounds, building on our groups recent results, before testing them in biological assays. 

You will join a supportive and collaborative group and receive training in a range of synthetic and analytical skills, including NMR, X-ray and Electron diffraction, photophysical characterisation and cell viability assays. 

The School of Chemistry and Chemical Engineering is committed to promoting equality, diversity inclusivity as demonstrated by our Athena SWAN award. We welcome all applicants regardless of their gender, ethnicity, disability, sexual orientation or age, and will give full consideration to applicants seeking flexible working patterns and those who have taken a career break.

The University has a generous maternity policy, onsite childcare facilities, and offers a range of benefits to help ensure employees’ well-being and work-life balance. The University of Southampton is committed to sustainability and has been awarded the Platinum EcoAward.