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Dr Jaswinder K Sethi BSc(Hons), DPhil(Oxon), FRSB

Principal Research Fellow in Immunometabolism, Welcome Trust Career Re-entry Fellow, Honorary NHS-Trust Research Fellow

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Dr Jaswinder K. Sethi is a Principal Research Fellow in Immunometabolism, a Wellcome Trust Career Re-entry Fellow and an honorary NHS Research Fellow based in the Faculty of Medicine at the University of Southampton

Dissecting how tissues sense, translate, and integrate nutritional cues is key to understanding healthy development and finding new therapeutic targets for treating obesity-linked metabolic diseases


Educated in London and graduated with first-class honours in biological sciences from Birkbeck College, University of London. This part-time degree was completed whilst maintaining a full-time technical research post at University College London. It also planted the seeds and mechanistic interests in cell communication. This led to a DPhil in calcium signalling from Oxford University, followed by postdoctoral training at Harvard University. Here she performed pioneering studies on molecular mechanisms linking obesity and insulin resistance with Gokhan Hotamisligil that catalysed the birth of a new field of research: Immunometabolism. Returning to the UK in 2000, Dr Sethi set up an independent research group at University of Cambridge to investigate Immunometabolic Signalling in Tissue Remodelling and Metabolic Disease. In 2017, the Sethi laboratory relocated to the University of Southampton and University Hospital Southampton NHS Foundation Trust.

Expertise: Immunometabolism, Cellular Signalling, Adipose Tissue Development & Biology, Tissue Remodelling, Metabolic Syndrome, Obesity, Type 2 Diabetes, Fatty Liver Disease, Cardiovascular Disease, Cancer

For more information see Dr Sethi’s Lab website at
Follow our Lab's latest news on Twitter @SethiLab.


BSc (Hons), Biological Sciences, Birkbeck College - University of London, 1993
DPhil (Oxon), Physiological Sciences, University of Oxford, 1997

Appointments held

Research Technician, University College London, 1989 – 1993

MRC PhD/DPhil Scholar, Oxford University, 1993 – 1996

US-UK Fulbright Scholar, Harvard University, 1997

Wellcome Trust Prize Postdoctoral Travelling Fellow (Outgoing), Harvard University, 1997 - 1999

Wellcome Trust Prize Postdoctoral Travelling Fellow (Returning), University of Cambridge, 2000 - 2001

Diabetes UK RD Lawrence Fellow, University of Cambridge, 2001

BBSRC David Phillips Research Fellow, University of Cambridge, 2002 – 2006

Senior Teaching Scholar in Medicine Trinity Hall, University of Cambridge, 
2004 – 2009

Honorary Researcher in Metabolic Medicine, Cambridge University NHS Trust, 2006 - 2014

Principal Investigator & Group Leader, University of Cambridge, 2007-2014

Visiting Professor, Università del Piemonte Orientale, Novara, Italy, 2014

Postdoctoral Fellows

Dr Sally Eaton (2018 - )

PhD Supervision

Ranmali Nawaratne PhD (Cantab), (2000 - 2004)
William P. Cawthorn PhD (Cantab), (2004 - 2008)
Meghana N. Patel PhD (Cantab), (2008 - 2012)

Josh Beavis (Soton), (2019 - )
Maria Kousetti (Soton), (2019 - )

Editorial Board Membership

Biochemical Journal, Portland Press (2006-2016)
Cell Biochemistry & Function, Wiley & Sons Ltd, (2007-2013)
International Journal of Obesity, NPG (2010-2016, 2016-date)
PLoS ONE, Public Library of Science (2010 - date)
Adipocyte, Taylor & Francis (Founding EB member, 2012-date)
iScience, Cell Press (Founding EB member, 2018 – date)

Funding Panel Membership

L'Agence nationale de la recherche (ANR), France (2013-2015)
Biotechnology and biological Sciences Research Council (BBSRC), UK (2016-date)

Other Professional Membership

Fellow of the Royal Society of Biology

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Book Chapters



MEDI6108 Modern Management of Diabetes, Nutrition and Pharmacology (MODNAP): Deputy module lead
BMedSci: Personal Academic Tutor
BM5: Supervisor of laboratory projects
PhD/MSc: Supervisor

Come work with us!

We are keen to share our enthusiasm for problem solving and biomedical discovery through lab-based research. In addition to advertised posts, we are open to applications from potential visiting researchers or postdoctoral fellows. Please contact Dr J. K. Sethi for more details.

Dr Jaswinder K Sethi
Institute of Developmental Sciences Building, Southampton University Hospital, Tremona Road, Southampton SO16 6YD
Office Tel: +44 (0)2381 208663

Room Number : SGH/IDS/MP887

Dr Jaswinder K Sethi's personal home page
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