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Mr Rahul Bhome MB BS, BSc (Hons), MRCS, MAcadMEd

MRC Clinical Research Training Fellow, Specialty Registrar in General Surgery

Mr Rahul Bhome's photo

Stromal-epithelial communication in the tumour microenvironment

Mr Bhome qualified in Medicine from UCL Medical School with distinction, having received a first class intercalated BSc in Pharmacology. His undergraduate research focussed on inflammatory signalling from adipose tissue and interleukin-6 generation in particular. Based on these achievements, he was appointed to an Academic Foundation post at Imperial College in 2010, followed by an NIHR Academic Clinical Fellowship in General Surgery at the University of Southampton in 2012. In 2015 he was awarded a Cancer Research UK Clinical Research Training Fellowship to complete a PhD under the supervision of Professor Alex Mirnezami at the Southampton CRUK Centre. This was supplemented by an MRC Clinical Research Training Fellowship in 2017.

Mr Bhome’s research interests are in the field of tumour microenvironment, specifically the crosstalk between stromal fibroblasts and cancer cells which drives disease progression. His project seeks to identify and functionally annotate exosomal microRNAs (exomiRs) in colorectal cancer. He has published several articles and book chapters on cancer stroma, exosomes and microRNAs and has presented at numerous international meetings. His work has received additional grant funding from the British Council (Nanoscience Fellowship) and the European Union (COST Fellowship), which has allowed him to visit and collaborate with researchers at Tel Aviv and Ghent universities.


BSc (First Class Honours), Medical Sciences with Pharmacology, UCL, 2007
MB BS (Distinction), Medicine and Surgery, UCL Medical School, 2010
MRCS, Royal College of Surgeons (England), 2012

Appointments held

CRUK Clinical Research Fellow
Specialty Registrar in General Surgery






Research interests

Tumour microenvironment; Cancer stroma; Exosomes; MicroRNAs

MPhil/ PhD Project (2015-): Investigating the role of exosomes in stromal-epithelial interaction in the colorectal tumour microenvironment.

Research group

Cancer Sciences

Affiliate research group

Dr Noam Shomron, Sackler Faculty of Medicine, Tel Aviv University

Examiner – Final/ Year 3 BM OSCE, University of Southampton Medical School (2014-)
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Book Chapters


Tutor/ Demonstrator, Southampton Surgical Society (2013-)
Mr Rahul Bhome
Faculty of Medicine, University of Southampton, Building 85, Life Sciences Building, Highfield Campus, Southampton, SO171BJ

Room Number: SGH/CSB/MP824

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