Project overview
The UKRMP2 Smart Materials Hub aims to develop the next generation of bioactive scaffolds and biomatrices to treat the eye, the musculoskeletal system and the liver. Regenerative medicine holds the promise of revolutionising patient care addressing the problems of an ageing population.
The Bone and Joint Research Group are part of the Acellular Smart Materials Hub with a specific focus on addressing skeletal repair and function moving from basic discovery science through to clinical translation. Research will seek to address the current unmet need for material systems that not only deliver cells safely but also provide cues for differentiation and the organisation of hierarchical and vascularised tissues. The development of materials with highly controlled spatio-temporal features that can respond to environmental triggers is also key in the quest for smarter more biomimetic solutions. The Acellular Smart materials UKRMP Programme will, over five years deliver innovative acellular material solutions to tissue regeneration with research encompassing fundamental research through to preclinical evaluation and, ultimately clinical delivery.
The Bone and Joint Research Group are part of the Acellular Smart Materials Hub with a specific focus on addressing skeletal repair and function moving from basic discovery science through to clinical translation. Research will seek to address the current unmet need for material systems that not only deliver cells safely but also provide cues for differentiation and the organisation of hierarchical and vascularised tissues. The development of materials with highly controlled spatio-temporal features that can respond to environmental triggers is also key in the quest for smarter more biomimetic solutions. The Acellular Smart materials UKRMP Programme will, over five years deliver innovative acellular material solutions to tissue regeneration with research encompassing fundamental research through to preclinical evaluation and, ultimately clinical delivery.
Staff
Lead researchers
Other researchers
Collaborating research institutes, centres and groups
Research outputs
Richard Oreffo, Laila A. Damiati, P. Monica Tsimbouri, Virginia Hernandez, Vineetha Jayawarna, Mark Ginty, Peter Childs, Y. Xiao, Karl Burgess, Julia Anne Wells, Mark R Sprott, R. Meek, Peifeng Li, Angela Nobbs, Gordon Ramage, Bo Su, Manuel Salmeron-Sanchez & Matthew J. Dalby,
2021, Biomaterials
Type: article
Benita, Scout MacKay, Karen Marshall, James Grant-Jacob, Janos Kanczler, Robert W. Eason, Richard Oreffo & Benjamin Mills,
2021, Biomedical Physics & Engineering Express, 7(5)
Type: article
Richard Oreffo, Babatunde O. Okesola, Ana Karen Mendoza-Martinez, Gianluca Cidonio, Burak Derkus, Delali Boccorh, David Osuna de la Pena, Sherif Elsharkawy, Yuanhao Wu, Jonathan Dawson, Alastair Wark, Dafna Knani, Dave J. Adams & Alvaro Mata,
2021, ACS Nano, 15(7), 11202–11217
Type: article