Project overview
This project aims to improve our understanding of the determinants and risk factors for low lung function, respiratory disability and the development of chronic obstructive lung disease (COPD), through exploitation of information held within existing cohorts and their population–based biobanks. Even though COPD has long been viewed as a predominantly smoking-related disease, more than 30% of people with COPD have never smoked, and there is increasing awareness that other risk profiles must contribute to disease. COPD is a major cause of disease, disability and death in European adults and lung function is a critical objective marker of good lung health, strongly associated with other major chronic diseases (for example, cardiovascular disease) and is a major independent determinant of overall health status (physical and mental health, quality of life, exercise capacity, independent living).
Staff
Lead researchers
Research outputs
Nils Oskar Jõgi, Cecilie Svanes, Silver Peeter Siiak, Erin Logan, John W. Holloway, Jannicke Igland, Ane Johannessen, Michael Levin, Francisco Gomez Real, Vivi Schlunssen, William G.C. Horsnell & Randi J. Bertelsen,
2018, Clinical & Experimental Allergy, 48(1), 66-77
DOI: 10.1111/cea.13055
Type: article
Matthew Machin, André F.S. Amaral, Matthias Wielscher, Faisal I. Rezwan, Medea Imboden, Marjo-Riitta Jarvelin, Ian M. Adcock, Nicole Probst-Hensch, John W. Holloway & Deborah L. Jarvis,
2017, BMC Pulmonary Medicine, 17(54)
Type: article