Brodzki EPSRC Joining the Dots

Project overview

Staff

Lead researcher

Professor Jacek Brodzki

Professor of Pure Mathematics

Connect with Jacek

Email: j.brodzki@soton.ac.uk

Other researchers

Professor Peter Smith BSc, PhD, MA, FRSB

Director of Institute Life Sciences

Connect with Peter

Email: p.j.smith@soton.ac.uk

Professor Jeremy Frey

Professor of Physical Chemistry

Connect with Jeremy

Email: j.g.frey@soton.ac.uk

Professor Ratko Djukanovic

Professor of Medicine

Research interests

Professor Djukanovic has a lifelong interest in asthma, especially its severe forms. where his focus is on: 1) underlying pathobiological mechanisms of asthma, 2) stratification of asthma into clinical phenotypes and mechanism-based endotypes, 3) unmet needs of severe asthma management. He also has an interest in the mechanisms and treatments of severe viral infections of the lung.
Underlying mechanisms of asthma: Professor Djukanovic has conducted pioneer studies into the pathology of asthma, applying research bronchoscopy (with endobronchial biopsy and bronchoalveolar lavage) and sputum induction. He led the initial task forces which defined the use of these two techniques, thereby paving the way for standardised research approches that enabled in-depth descriptions of the roles of various inflammatory cells and their mediators. He developed an explant model, consisting of bronchial biopsies placed into tissue culture, that could be stimulated ex vivo with relevant triggers, applying as needed, novel agents not yet approved for in vivo use in humans volunteers.

Connect with Ratko

Email: rd1@soton.ac.uk

Professor Mahesan Niranjan

ISIS Chair

Connect with Mahesan

Email: mn@ecs.soton.ac.uk

Collaborating research institutes, centres and groups

Institute for Life Sciences

We bring together expertise in research and education from different disciplines to create scientific opportunities and address important issues in health, society and enterprise.