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Research project

Computational modelling to evaluate, understand and predict the placental transfer of xenobiotics as an integrated system

Lead researcher:
Research funder:
Biotechnology & Biological Sciences Research Council
Not active


Lead researcher

Doctor Bram Sengers

Associate Professor

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Other researchers

Professor Xunli Zhang PhD, DIC, FRSC, CChem, CEng

Head of Department-Chemical Engineerg

Research interests

  • Xunli’s key expertise lies in the area of microfluidics technology from design and fabrication of microfluidic devices, through the development of in-situ monitoring methods for bio/chemical processes, to microfluidic modelling, microsystems integration and automation. The application is largely associated with biomedical challenges like patient specific design of microfluidic devices for cancer treatment, rapid diagnosis, and tackling antimicrobial resistance (AMR). The continuous flow reactors have been used for the synthesis of a range of nanoparticles, both organic and inorganic, for application in drug delivery and energy saving. The technologies developed in his research have also found great potential for industrial applications through a variety of industrial collaborations. 

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Professor Rohan Lewis PhD, FTPS

Prof of Placental&Integrative Physiolgy

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Doctor Jane Cleal PhD

Lecturer in Reproductive Cell Biology

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Research outputs

Benjamin Mills,
Benita, Scout MacKay,
, 2022
Type: conference
& Bram Sengers
, 2020 , Placenta , 93 , 43--48
Type: review
Emma M. Lofthouse,
& Rohan M. Lewis
, 2018 , The Journal of Physiology , 596 (23) , 5511--5522
Type: review
Emma M Lofthouse,
Ita M O'Kelly,
Bram G Sengers,
, 2018 , Biochemical and Biophysical Research Communications
Type: article
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