Research project

The role of Factor inhibiting HIF (FIH) in the development of idiopathic pulmonary fibrosis (IPF)

Research groups:
Lead researcher:

Dr Yihua Wang
Research funder:

The Academy of Medical Sciences
Status:

Not active

Staff

Lead researcher

Dr Yihua Wang

Associate Professor

Research interests

Cell Signalling in Disease
Epithelial-Mesenchymal Crosstalk
Pulmonary Fibrosis

Connect with Yihua

Email: yihua.wang@soton.ac.uk

Collaborating research institutes, centres and groups

Cell and Developmental Biology

We explore how molecular interactions between proteins and small molecules, defined at atomic resolution, govern biochemical output and in turn control cell behaviour.

Research outputs

Nuclear entry and export of FIH are mediated by HIF1α and exportin1, respectively

Yihua Wang,

Shan Zhong,

Christopher J. Schofield,

Peter J. Ratcliffe,

& Xin Lu

, 2018 , Journal of Cell Science , 131 (22) , 1--8

DOI: 10.1242/jcs.219782

Type: article