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Southampton Health Technology Assessments CentreNews

Two new SHTAC research articles featured in the latest issue of the International Journal of Technology Assessment in Health Care

Published: 7 November 2012
Treatment of hepatitis C

Research articles on the cost-effectiveness of behavioural interventions to prevent sexually transmitted infections, and on anti-viral treatment for hepatitis C have recently been published in the journal.

The latest issue of the International Journal of Technology Assessment in Health Care features two articles reporting SHTAC's research into infectious diseases. One article reports the results of a cost-effectiveness analysis of school-based behavioural interventions to prevent sexually transmitted infections (STIs) in young people. The prevention of STIs and teenage pregnancy is a high priority for health policy due to the adverse impact on both individuals and health service resources. The study, based on a systematic review and economic model, found that cost-effectiveness was uncertain due to the limited effect of the behavioural interventions on sexual behaviour and infection rates, and lack of data for some aspects of the economic model.

The second article investigated the clinical-effectiveness and cost-effectiveness of shortened duration of peginterferon alfa and ribavirin combination therapy for adults with chronic hepatitis C. A reduction in the length of treatment is considered to be advantageous as it may spare patients adverse effects associated with antiviral treatment, and may potentially reduce health care costs. A systematic review and economic evaluation was conducted comparing standard duration with shortened treatment. It was found that shortened treatment resulted in cost savings, but in some scenarios also resulted in poorer outcomes for patients in terms of clearing the virus, compared with standard treatment.

For further detail on SHTAC's research into infectious diseases please visit our Research page.

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