About
Sarah Ennis - Professor of Genomics at the University of Southampton, has worked in the field of genetic epidemiology for over 20 years; runs the Human Genomic Informatics (HGI) Group dry laboratory specialising in the analysis of NGS data in clinical cohorts; and has published over 200 papers with focus on underpinning the molecular genetic basis of human rare and common disease. Sarah is chief investigator of cohort studies recruiting NHS patients and leads projects analysing Genomics England and UKBioBank data. Projects include optimisation and cleaning of digitally extracted NHS data, execution of contemporary sequencing of DNA and RNA from patient samples and integration of data from multiple ‘omic sources using machine learning approaches to inform clinical management. In her role as Research Director for the Genomics Medicine Service Alliance, she facilitates clinical research pathways to optimise patient genomic data for better health outcomes. Sarah is theme lead for Human Genetics and Genomic Medicine in the school of Human Development and Health.
Sarah Ennis holds several significant external roles that extend her impact beyond the University of Southampton:
- She is Research Director within the Central and South Genomic Medicine Service Alliance, a national body that oversees the implementation of genomic testing pathways across the NHS, ensuring the integration of genomic data into clinical care
- She serves as Chief Investigator on multiple NIHR portfolio studies, leading large-scale clinical research projects that recruit thousands of patients and families to advance genomic medicine
- She also holds an honorary NHS contract, working closely with clinical teams across various NHS Trusts to bridge research and clinical practice
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