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Lown/Little - SPCR - Optimising Treatment for Mild Systolic hypertension in the Elderly (OPTIMISE)
This study is now complete, please see associated publications. This is a Primary Care based, open label, randomised controlled trial with embedded qualitative components and the aims are: To safely reduce the amount of blood pressure medication take...
Little - NIHR PGfAR - REducing Common infections in Usual practice for Recurrent respiratory tract infections (RECUR) (November 2017)
The National Institute for Health Research (NIHR) has funded the RECUR Programme to develop and test interventions to find out if they can reduce the frequency, severity and duration of respiratory infections (such as colds, sore throats, sinus, ches...
Lown - NIR PGfAR (via Cambridge) - Screening for Atrial Fibrillation (Aug 17)
Atrial fibrillation (AF) is a heart condition that causes an irregular heartbeat. It affects up to 1 in 10 people over the age of 65 but does not necessarily cause symptoms. Having atrial fibrillation increases the risk of having a stroke 5-fold, but...
Everitt - NIHR HTA - Amitriptyline at low-dose and titrated for irritable bowel syndrome as second-line treatment (The ATLANTIS Study): A double-blind placebo controlled trial
We want to find out whether a tablet called amitriptyline helps people with irritable bowel syndrome (IBS). Amitriptyline will be prescribed by a GP, at a low dose, when other treatments (e.g. changes to diet) have not worked. We are interested in it...