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The University of Southampton

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Research in progress

SHTAC is currently working on a wide range of projects.

Where available, click the link below for further information on each project.

Technology Assessment Reports for NICE

Project	Estimated publication date
Perineal biopsy devices for diagnosis of prostate cancer in people with suspected prostate cancer	2022
Eladocagene exuparvovec for treating aromatic L-amino acid decarboxylase deficiency ID3791	2023
Mavacamten for symptomatic obstructive hypertrophic cardiomyopathy	2023
Daratumumab combination for previously treated multiple myeloma	2023
Darolutamide with androgen deprivation therapy and docetaxel for treating hormone-sensitive metastatic prostate cancer [ID3971]	2023
Mirikizumab for treating moderately to severely active ulcerative colitis	2023
Ruxolitinib for polycythaemia vera (review of TA356)	2023
Efgartigimod for treating generalised myasthenia gravis ID4003	2023

Research - Other projects

Project	Funder	SHTAC Contact
CONFIRM - Checkpoint blockade for inhibition of relapsed mesothelioma: A phase III trial to evaluate the efficacy of nivolumab in relapsed mesothelioma	Cancer Research UK	Prof Joanne Lord
EACH-B - Engaging adolescents in changing behaviour	NIHR Programme Grant for Applied Research	Prof Joanne Lord
CASA-AF - Catheter ablation versus thoracoscopic surgical ablation in long standing persistent atrial fibrillation	NIHR Efficacy and Mechanism Evaluation Programme	Prof Joanne Lord
Endobarrier - Controlled trial of a duodenal sleeve bypass device (Endobarrier) compared with standard medical therapy for the management of obese subjects with type 2 diabetes	NIHR Efficacy and Mechanism Evaluation Programme	Prof Joanne Lord
ATTACK - Aspirin To Target Arterial Events in Chronic Kidney Disease	NIHR Health Technology Assessment Programme & British Heart Foundation	Prof Joanne Lord
Nudging healthier dietary habits: evaluation of a supermarket placement strategy in the WRAPPED study	NIHR Public Health Research Programme	Prof Joanne Lord
EMPRESS: A feasibility study of Very Early Mobilisation PRogrammES in Critical Care	NIHR Research for Patient Benefit Programme	Maria Chorozoglou
FAIR - FLAGELLIN AEROSOL THERAPY AS AN IMMUNOMODULATORY ADJUNCT TO THE ANTIBIOTIC TREATMENT OF DRUG-RESISTANT BACTERIAL PNEUMONIA	European Commission Horizon 2020 Framework Programme	Prof Joanne Lord & Dr Jo Picot
Pathways to Health Through Cultures of Neighbourhoods	Arts Humanities Research Council	Neelam Kalita
Sleep problems in Child and Adolescent ADHD - Development and evaluation of an NHS clinical management pathway and digital intervention for core sleep problems	NIHR	Prof Joanne Lord
Real-world Implementation and Evaluation of an AI decision support software (ArtiQ.Spiro) into primary care respiratory diagnostic pathways	NIHR AI in Health and Care Award	David Scott
Wearable Textile with Integrated Electrotherapy and Sensing for Joint Pain Management	Medical Research Council	David Scott

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