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The University of Southampton
Southampton Health Technology Assessments Centre

Research in progress

SHTAC is currently working on a wide range of projects. 

Where available, click the link below for further information on each project.

Technology Assessment Reports for NICE 

 

ProjectEstimated publication date 

Solriamfetol fortreating excessive waketime sleepiness caused by obstructive sleep apneoa 

2022

Daratumumab in combination for untreated multiple myeloma when stem cell transplant is suitable 

2022

Update of DG23 PlGF-based testing to help diagnose suspected pre-eclampsia 

2022

Perineal biopsy devices for diagnosis of prostate cancer in people with suspected prostate cancer

2022

Tucatinib with trastuzumab and capecitabine for treating HER2-positive locally advanced or metastatic breast cancer after 2 or more anti-HER2 therapies 

2022

Semaglutide for managing overweight and obesity

2022

Faricimab for treating diabetic macular oedema

2022

Avalglucosidase alfa for treating Pompe disease

2022

Cemiplimab for treating cutaneous squamous cell carcinoma (CDF review of TA592)

2022

 

Research - Other projects

 Project

Funder

SHTAC Contact

Interventions for encouraging sexual behaviours intended to prevent cervical cancer (Cochrane systematic review update)                                 SHTAC Dr Jonathan Shepherd
CONFIRM - Checkpoint blockade for inhibition of relapsed mesothelioma: A phase III trial to evaluate the efficacy of nivolumab in relapsed mesothelioma Cancer Research UK Prof Joanne Lord
EACH-B - Engaging adolescents in changing behaviour NIHR Programme Grant for Applied Research   Prof Joanne Lord
CASA-AF - Catheter ablation versus thoracoscopic surgical ablation in long standing persistent atrial fibrillation

NIHR Efficacy and Mechanism  Evaluation Programme  Prof Joanne Lord
Endobarrier - Controlled trial of a duodenal sleeve bypass device (Endobarrier) compared with standard medical therapy for the management of obese subjects with type 2 diabetes NIHR Efficacy and Mechanism  Evaluation Programme  Prof Joanne Lord
ATTACK - Aspirin To Target Arterial Events in Chronic Kidney Disease NIHR Health Technology Assessment Programme & British Heart Foundation Prof Joanne Lord

Optimising Cardiac Surgery ouTcOmes in People with diabeteS (OCTOPuS)

NIHR Health Technology Assessment Programme Dr Jo Picot

Nudging healthier dietary habits: evaluation of a supermarket placement strategy in the WRAPPED study

NIHR Public Health Research Programme Prof Joanne Lord

A feasibility trial of serial prophylactic exchange blood transfusion (SPEBT) in pregnant women with sickle cell disease (SCD) aiming to improve maternal and infant outcomes 

NIHR Research for Patient Benefit Programme Maria Chorozoglou

EMPRESS: A feasibility study of Very Early Mobilisation PRogrammES in Critical Care

NIHR Research for Patient Benefit Programme Maria Chorozoglou

Rapid review of the effectiveness of digital tools to improve recruitment and retention of participants in randomised controlled trials in health

NIHR CTU Support Funding Dr Jonathan Shepherd & Dr Geoff Frampton

FAIR - FLAGELLIN AEROSOL THERAPY AS AN IMMUNOMODULATORY ADJUNCT TO THE ANTIBIOTIC TREATMENT OF DRUG-RESISTANT BACTERIAL PNEUMONIA

European Commission Horizon 2020 Framework Programme Prof Joanne Lord & Dr Jo Picot
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