The University of Southampton
Medicine

Mr Jay Self BM, FRCOphth, PhD

Associate Professor and Consultant Ophthalmologist

Mr Jay Self's photo
Related links

Mr Self is a joint Academic/Clinical Ophthalmologist who works as a Consultant Ophthalmologist at Southampton General Hospital and runs a group at the University of Southampton as an Associate Professor. He completed his higher specialist training in Paediatric Ophthalmology in Southampton and Manchester and his research training through an MRC Clinical Research Training Fellowship/PhD in Ophthalmic Molecular Genetics. He has an interest in translation of basic science findings into clinical practice in Paediatric Ophthalmology and has published widely in addition to writing book chapters and documents for the Royal College of Ophthalmologists. He is a medical advisor for 3 charities, is a board member for a third and sits on the University Hospital Southampton charity committee. He has a particular research interest in nystagmus and genetic eye diseases and has a focus on improving the lives of children and families with eye disease. He also works with both local and national community groups and schools in order to promote public awareness of eye diseases affecting children.

Mr Self is a joint Academic/Clinical Ophthalmologist who works as a Consultant Paediatric Ophthalmologist at Southampton General Hospital and as a Senior Lecturer at the University of Southampton. He completed his higher specialist training in Paediatric Ophthalmology in Southampton and Manchester and his research training through an MRC Clinical Research Training Fellowship/PhD in Ophthalmic Molecular Genetics. He has an interest in translation of basic science findings into clinical practice in Paediatric Ophthalmology and has published widely in addition to writing book chapters and documents for the Royal College of Ophthalmologists. He is a medical advisor for two charities and as a board member for a third. He has a particular research focus in the group of disorders collectively termed congenital Nystagmus and utilizes genetic techniques, eye tracking technology and modeling to achieve his aim of improving the lives of children and families with this disorder. He also works with both local and national community groups and schools in order to promote public awareness and engagement in science.

Qualifications

BM University of Southampton (1999)
PhD University of Southampton (2009)
FRCOphth Royal College of Ophthalmologists (2012)

Appointments held

Present – Senior Lecturer and Honorary Consultant Ophthalmologist. University of Southampton

2011 – 2012 Fellow in Paediatric Ophthalmology, Manchester Royal Eye Hospital.

2008 – 2011 Senior Trainee and Honorary Visiting Lecturer, University of Southampton.

2005 – 2008 MRC Clinical Research Training Fellow and PhD student, University of Southampton.

2002-2005 Trainee in Ophthalmology. University of Southampton and Wessex deanery rotation.

Research

Responsibilities

Publications

Teaching

Contact

Research interests

Mr Self is a Consultant Ophthalmologist and a Senior Lecturer. As a clinical academic he is particularly interested in translation of research findings into meaningful benefit for his patients. He has a particular clinical interest in paediatric genetic eye disease including nystagmus and congenital cataract.

His research interests are accordingly tailored towards nystagmus and translational genetics and he continues to prioritize his research according to the needs as identified by patients through his work with three vision support charities and his dedication to a public engagement in science program. He benefits from significant collaboration both within the university and the Universities of Plymouth, Bristol, Cardiff, Manchester and worldwide.

Nystagmus

Nystagmus is a disorder characterized by uncontrolled to-and-fro movement of the eyes, is associated with poor vision and affects approximately 1:1500 people. Many causes of Nystagmus are known however currently most patients only receive a descriptive diagnosis, repeated underestimation of their visual problems, and no specific treatments.

Mr Self aims to address these shortfalls using a variety of research methods and utilizing expertise and collaboration from a wide range of disparate disciplines.

Nystagmus Diagnosis

Mr Self has amassed some of the largest cohorts of patient with nystagmus in the world and is using next-generation sequencing techniques to unpick the heterogeneity of presumed idiopathic nystagmus. He hopes to use this information to explore the complex underlying pathophysiologies in addition to working towards a clinically useful genetic test for use in clinics and to aid preparation for robust clinical trials in genetically distinct cohorts. He strives to counter a one-size-fits-all approach to nystagmus.

Nystagmus Phenotyping

Mr Self uses eye-tracking equipment to study the waveform details of patients with nystagmus and other oculo-motor disorders.

QUOTE from Nystagmus Network secretary: "Time and again I hear from people with nystagmus (and know from my own experience) that their everyday vision just does not live up to the measured vision or expectations of their optometrists. They just don’t measure the things we have difficulty with"

By using the latest generation of non-contact eye trackers, Mr Self is developing methods to test the specific real world problems identified by patients (e.g. the ‘Time to see phenomenon’) in order to quantify the disability for the first time in children and to prepare robust outcome measures for clinical trials.

Nystagmus model development

Mr Self is developing a model in order to identify the underlying pathophysiologies in nystagmus in addition to optimizing a model for treatment development.

Other projects

Mr Self also performs a number of research projects from the Eye Department at Southampton General Hospital including phase 1 and 3 drug trials and clinical research projects for a variety of paediatric ophthalmic conditions.
Mr Self also supports charities who provide and research the provision of eye care in developing countries.

Examining a child in clinic
Examining a child in clinic
The role of genetic testing
Genetic testing
Eye tracking with children
Eye tracking with children
image Eye tracking with children
Eye tracking with children

Academic unit(s)

Clinical and Experimental Sciences Academic Units

Affiliate academic unit(s)

Clinical Neuroscience Research group

Teach on Regional ophthalmology PG program

Invited speaker for teaching programs outside of region

Teach on BM4 and BM5 course

Lead Ophthalmologist for oculo-genetics service at SUHT

Lead Paediatric Cataract service at SUHT

Advisor to INvision research charity

Board member of Gift of Sight charity

Lecturer and examiner for UHS NNP course

Articles

Book Chapters

Conferences

Major contributor to the Wessex Regional Ophthalmology Postgraduate teaching program.

Teaches on the BM4 and BM5 medical degree courses at the University of Southampton

Writes examination questions, teaches and examines on the University of Southampton neonatal Nurse Practitioner training program.

Teaches both Paedaitric and adult surgical techniques to junior Ophthalmology trainees in his role as an NHS Consultant.

Mr Jay Self
Tel: +44 (0)23 8120 3617 E-mail: jes3@southampton.ac.uk

Room Number:SGH/LD67/MP806

Share this profile Share this on Facebook Share this on Google+ Share this on Twitter Share this on Weibo

We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we will assume that you are happy to receive cookies on the University of Southampton website.

×