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Research project

Investigation of Mechanotransduction in Tuberculosis in Search of Therapeutic Targets

Staff

Lead researchers

Dr Liku Tezera BM, MSc , PhD, FHEA

Senior Research Fellow
Research interests
  • Physiologically relevant in vitro models for chronic bacterial infections that capture host mechanics and microenvironments.TB granuloma mechanobiology.Mechanotransduction pathways, including YAP/TAZ, SRF/MRTF, integrins and TRP channels.Host-directed therapy screening across defined stiffness states.Validating 3D models against patient samples to reduce animal use
Connect with Liku

Email: L.Tezera@soton.ac.uk

Research outputs