Open menu
View all research projects
Research project

S Khakoo: Using MHC Class l Peptides to modulate NK cell activity, as a basis for immunotherapy

Staff

Lead researcher

Professor Salim Khakoo

Professor of Hepatology

Research outputs

Anti-viral responses of tissue-resident CD49a+ lung NK cells are dysregulated in COPD
Grace Elizabeth Cooper,
Jemma Mayall,
Chantal Donovan,
Tatt J. Haw,
Kurtis F. Budden,
Nicole G. Hansbro,
Evy E. Blomme,
Tania Maes,
Chia Wei Kong,
Jay C. Horvat,
Salim I. Khakoo,
Tom MA Wilkinson,
Philip M. Hansbro,
& Karl J. Staples
, 2022 , American Journal of Respiratory and Critical Care Medicine
DOI: 10.1164/rccm.202205-0848OC
Type: article
KIR2DS2 expression identifies NK cells with enhanced anticancer activity
Matthew Blunt,
Mark Cragg,
Amber Doyle,
Jack, Graham Fisher,
Salim Khakoo,
Francesco Forconi,
Peter Johnson,
Marta Ewa Polak,
Lara, Victoria Graham,
Andres Vallejo Pulido,
Rebecca Fulton,
& Matthew Carter
, 2022 , The Journal of Immunology , 209 (2) (2) , 379--390
DOI: 10.4049/jimmunol.2101139
Type: article
Natural killer cells and regulatory T cells cross talk in hepatocellular carcinoma: exploring therapeutic options for the next decade
Amber G. Bozward,
Frazer Warricker,
Ye H. Oo,
& Salim I. Khakoo
, 2021 , Frontiers in Immunology , 12
DOI: 10.3389/fimmu.2021.643310
Type: review
Selinexor enhances NK cell activation against malignant B cells via downregulation of HLA-E
Jack, Graham Fisher,
Salim Khakoo,
Mark Cragg,
Francesco Forconi,
Peter Johnson,
Amber Doyle,
christopher Walker,
yosef landesman,
& Matthew Blunt
, 2021 , Frontiers in Oncology
DOI: 10.3389/fonc.2021.785635
Type: article
A peptide: MHC based DNA vaccination strategy to activate natural killer cells by targeting killer cell immunoglobulin-like receptors.
Salim Khakoo,
Pauline E Rettman,
Matthew Blunt,
Rebecca Fulton,
Andres Vallejo Pulido,
Leidy Bastidas Legarda,
Laura Espana-Serrano,
Marta Polak,
Aymen Al-Shamkhani,
& Christelle Retiere
, 2021 , Journal for Immunotherapy of Cancer , 9 (5)
DOI: 10.1136/jitc-2020-001912
Type: article
Back to top