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Research project

S Khakoo: Using MHC Class l Peptides to modulate NK cell activity, as a basis for immunotherapy

Staff

Lead researcher

Professor Salim Khakoo

Professor of Hepatology

Research outputs

Disruption of the NKG2A:HLA-E immune checkpoint axis to enhance NK cell activation against Cancer
Jack G. Fisher,
Amber D. P. Doyle,
Lara V. Graham,
Salim I. Khakoo,
& Matthew D. Blunt
, 2022 , Vaccines , 10 (12)
DOI: 10.3390/vaccines10121993
Type: article
Anti-viral responses of tissue-resident CD49a+ lung NK cells are dysregulated in COPD
Grace Elizabeth Cooper,
Jemma Mayall,
Chantal Donovan,
Tatt J. Haw,
Kurtis F. Budden,
Nicole G. Hansbro,
Evy E. Blomme,
Tania Maes,
Chia Wei Kong,
Jay C. Horvat,
Salim I. Khakoo,
Tom MA Wilkinson,
Philip M. Hansbro,
& Karl J. Staples
, 2022 , American Journal of Respiratory and Critical Care Medicine
DOI: 10.1164/rccm.202205-0848OC
Type: article
KIR2DS2 expression identifies NK cells with enhanced anticancer activity
Matthew Blunt,
Mark Cragg,
Amber Doyle,
Jack, Graham Fisher,
Salim Khakoo,
Francesco Forconi,
Peter Johnson,
Marta Ewa Polak,
Lara, Victoria Graham,
Andres Vallejo Pulido,
Rebecca Fulton,
& Matthew Carter
, 2022 , The Journal of Immunology , 209 (2) (2) , 379--390
DOI: 10.4049/jimmunol.2101139
Type: article
The role of NK cells in oncolytic viral therapy
Frazer Warricker,
Salim I. Khakoo,
& Matthew D. Blunt
, 2021 , Journal of Translational Genetics and Genomics , 5 , 304--322
DOI: 10.20517/jtgg.2021.27
Type: article
Natural killer cells and regulatory T cells cross talk in hepatocellular carcinoma: exploring therapeutic options for the next decade
Amber G. Bozward,
Frazer Warricker,
Ye H. Oo,
& Salim I. Khakoo
, 2021 , Frontiers in Immunology , 12
DOI: 10.3389/fimmu.2021.643310
Type: review
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