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The University of Southampton
Engineering
Phone:
(023) 8059 2367
Email:
X.Niu@soton.ac.uk

Dr Xize Niu PhD

Associate Professor

Dr Xize Niu's photo

Dr Xize Niu is Associate Professor within Engineering and Physical Sciences at the University of Southampton.

Xize's group is currently focused on scientific and engineering challenges in developing wearable/portable sensors for healthcare and environmental applications, especially for real time and continuous monitoring of chemical variations in body or environmental fluids. The key research areas related are microfluidics, lab-on-a-chip, analytical chemistry and mechatronics.

There are openings in his group for PhD studies and postdoctoral research (wearable healthcare sensor, or environmental sensor). Applications are welcome.

Research interests

Dr. Niu is interested in engineering microfluidic devices for bio- analytical applications, such as handling minute amount of liquid samples, and performing high throughput and in situ analysis. Consequently his research covers:

  • Biosensors and wearable technologies;
  • Protein and DNA analysis;
  • Therapeutic drug monitoring, Drug development and screening;
  • Microfluidics and lab-on-a-chip;
  • MEMS, micro and nano technology;
  • Fluid mechanics, multiphase phase flows and droplets.

He likes to cover a project from the fundamental science through to application and product. He has applied 7 patents, formed 2 spin-out companies, and a few of his inventions have been commercialised to products.

Group members
Dr. Adrian Nightingale (Research Fellow)
Dr. Gareth Evans (Research Fellow)
Dr. Sharon Coleman (Technical Officer)
Wahida Bhuiyan (PhD student)
Juan Avilés (PhD student)
Sel Gultekin (PhD student)

Nature Chemistry book cover
Dr Xize Niu's research
Mitos
Dr Xize Niu's research
Water Sensor
Water Sensor
Wearable Sensor
Wearable Sensor

Research group

Mechatronics Engineering Group

Affiliate research group

Bioengineering Science

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Articles

Conferences

Patent

Reviews

FEEG1004-29853 Electrical and Electronics Systems
FEEG2001-31292
Systems Design and Computing
FEEG3003-32772
Individual Project
SESM6021-28551
Introduction to Energy Technologies

Droplet Microfluidics

Droplets are defined here as water droplets dispersed in an immiscible oil phase or oil droplets dispersed in water. These droplets are contained and motivated through microfluidic conduits having dimensions most easily measured in microns. Droplets microfluidics is emerging as a reliable engineering tool for performing biological operations such as analyte encapsulation, sampling, metering, dilution, reaction, separation and detection.

In Niu’s lab, we are interested in studying droplet generation-on-demand. These studies have led to several publications and two patents, one for robotic droplet generation for lab usages that has been commercialised (DropixTM), and the latest one for sampling droplets from real environments such as body or environmental fluids, which has the potential to be developed into various healthcare and diagnostic devices or environmental sensors.

We are also interested in analysing biochemical molecules with droplet interfaced electrophoresis separation, liquid chromatography and mass spectrometry, or sensitive assays within droplets. For example we have recently developed droplet interfaced parallel separations that can incorporate hundreds of droplets and separation channels onto a single chip, enhancing analytical throughput and reducing sample consumption.

Novel droplet operation units and toolkit are also within our research interests. We have developed microfluidic chips for droplet merging, dilution and sorting etc. (and some of the chips have been commercialised).

Separation of biomolecules
Separation of biomolecules
Droplet on demand
Droplet on demand
Droplet trapping and merging
Droplet trapping and merging
Droplet dilution
Droplet dilution
Dr Xize Niu
Engineering, University of Southampton, Highfield, Southampton. SO17 1BJ United Kingdom

Email: X.Niu@soton.ac.uk

Room Number: 7/5013

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