Phone:: (023) 8059 5099
Email:: XL.Zhang@soton.ac.uk

Dr Xunli Zhang BEng MEng PhD FRSC AMIChemE CChem

Reader, Bioengineering Group, Deputy Director of Graduate School

Related links: Personal homepage

Dr Xunli Zhang is Reader, Bioengineering Group and the Deputy Director of Graduate School within Engineering and the Environment at the University of Southampton.

Xunli Zhang graduated from Northwest University (Xi'an, China), where he received his B.Eng. and M.Eng. in Chemical Engineering. Upon obtaining an ORS Award from the UK government, he started his Ph.D. studies at Imperial College London in October 1996, under the supervision of Professor Michael Mingos (FRS), and was awarded a Ph.D. degree by the University of London in May 2000. Subsequently, he worked as a postdoctoral research associate in the University of Hull with Professor Steve Haswell on miniaturised Lab-on-a-Chip technology. During this period he has also spent time as a senior scientist at Micro Chemical Systems Ltd. In August 2007, he joined the Faculty of Engineering and the Environment at the University of Southampton upon appointment to an RCUK (Research Councils UK) Academic Fellowship.

Research

Publications

Teaching

Contact

With a strong cross-disciplinary research background and experience at the interface of chemistry, chemical engineering and life sciences, Xunli’s current research interests are primarily centred around the development of microfluidic and Lab-on-a-Chip technologies and their applications in bioengineering. His research topics cover:

Cell-based bioanalysis, using microfluidic and Lab-on-a-Chip methodologies to manipulate and analyse single cells.

Drug delivery systems, synthesised with continuous-flow microfluidic reactors for controllable size and shape.

Biomicrofluidics for therapeutic applications including chemo/embolisation, ureteric stenting, and sclerosis of varicose veins.

Nano prisms, synthesised with continuous-flow microfluidic reactors for controllable optical properties

Research group

Bioengineering Science

Affiliate research group

Engineering Materials

Research project(s)

Organic nanoparticles for drug delivery – size matters

Making drug-loaded nanoparticles in a controllable way with uniform size or a narrow size range is crucial for their use as nanomedicine.

Blocking blood supply to starve cancerous tumours

Microfluidic technology can potentially provide a platform for evaluation of clinical and patient-specific features for cancer therapy, while as an alternative to animal models to reduce the amount of animal tests.

Nanoparticles for energy saving glazing

Nanoparticle based coating is a step towards energy saving glazing.

Rapid Diagnosis of Allergy to Drugs using a Microfluidic Platform

The aim of this project is to develop a microfluidics-based system for rapid diagnosis of allergy to drugs by integrating cross-disciplinary expertise of microfluidic bioengineering and medicine. This system will require small volumes of blood and provide a cost effective and reliable diagnostic test to determine drug allergy in patients. The study will focus on the separation and activation of human basophils, granulocytic cells which release histamine amongst other mediators in response to a drug allergen.

Articles

Bielecka, M. K., Tezera, L. B., Zmijan, R., Drobniewski, F., Zhang, X., Jayasinghe, S., & Elkington, P. (2017). A bioengineered three-dimensional cell culture platform integrated with microfluidics to address antimicrobial resistance in tuberculosis. mBio, 8(1), 1-14. [e02073-16]. DOI: 10.1128/mBio.02073-16

Caine, M., McCafferty, M. S., McGhee, S., Garcia, P., Mullett, W. M., Zhang, X., ... Lewis, A. L. (2017). Impact of yttrium-90 microsphere density, flow dynamics, and administration technique on spatial distribution: analysis using an in vitro model. Journal of Vascular and Interventional Radiology, 28(2), 260-268.e2. DOI: 10.1016/j.jvir.2016.07.001

Caine, M., Carugo, D., Zhang, X., Hill, M., Dreher, M. R., & Lewis, A. L. (2017). Review of the development of methods for characterization of microspheres for use in embolotherapy: translating Bench to Cathlab. Advanced Healthcare Materials. DOI: 10.1002/adhm.201601291

Carugo, D., Ankrett, D. N., Zhao, X., Zhang, X., Hill, M., O'Byrne, V., ... Lewis, A. L. (2016). Benefits of olidocanol endovenous microfoam (Varithena®) compared with physician compounded foams. Phlebology, 31(4), 283-295. DOI: doi:10.1177/0268355515589063

Stulz, E., Zhang, X., Carravetta, M., & Carboni, M. (2016). Efficient NIR light blockage with matrix embedded silver nanoprism thin films for energy saving window coating. Journal of Materials Chemistry C, 1-5. DOI: 10.1039/C6TC00026F

Hassan, S., Morgan, H., Zhang, X., & Niu, X. (2015). Droplet interfaced parallel and quantitative microfluidic-based separations. Analytical Chemistry, 1-7. DOI: 10.1021/ac504695w

Henry, C., Bolien, D., Ibanescu, B., Bloodworth, S., Harrowven, D. C., Zhang, X., ... Whitby, R. J. (2015). Generation and trapping of ketenes in flow. European Journal of Organic Chemistry, 2015(7), 1491-1499. DOI: 10.1002/ejoc.201403603

Carugo, D., Capretto, L., Roy, B., Carboni, M., Caine, M., Lewis, A. L., ... Zhang, X. (2015). Spatiotemporal dynamics of doxorubicin elution from embolic beads within a microfluidic network. Journal of Controlled Release, 214, 62-75. DOI: 10.1016/j.jconrel.2015.07.003

Bose, N., Zhang, X., Maiti, T. K., & Chakrab, S. (2015). The role of acoustofluidics in targeted drug delivery. Biomicrofluidics, 9(5), 052609-[17pp]. DOI: 10.1063/1.4928947

Carugo, D., Ankrett, D., O'Byrne, V., Wright, D., Lewis, A., Hill, M., & Zhang, X. (2015). The role of clinically-relevant parameters on the cohesiveness of sclerosing foams in a biomimetic vein model. Journal of Materials Science Materials in Medicine, 26(11), 1-10. DOI: 10.1007/s10856-015-5587-z

Bai, Y., Zhang, Q., Jia, P., Yang, L., Sun, Y., Nan, Y., ... Zheng, X. (2014). Improved process for pilot-scale synthesis of danshensu ((±)-DSS) and its enantiomer derivatives. Organic Process Research & Development, 18(12), 1667-1673. DOI: 10.1021/op4002593

Zmijan, R., Carboni, M., Capretto, L., Stulz, E., & Zhang, X. (2014). In situ microspectroscopic monitoring within a microfluidic reactor. RSC Advances, 4(28), 14569-14572. DOI: 10.1039/c4ra01650e

Clavica, F., Zhao, X., ElMahdy, M., Drake, M., Zhang, X., & Carugo, D. (2014). Investigating the flow dynamics in the obstructed and stented ureter by means of a biomimetic artificial model. PLoS ONE, 9(2), 1-12. DOI: 10.1371/journal.pone.0087433

Carugo, D., Capretto, L., Nehru, E., Mansour, M., Smyth, N., Bressloff, N., & Zhang, X. (2013). A microfluidic-based arteriolar network model for biophysical and bioanalytical investigations. Current Analytical Chemistry, 9(1), 47-59. DOI: 10.2174/157341113804486437

Carugo, D., Ankrett, D. N., O'Byrne, V., Willis, S., Wright, D., Lewis, A., ... Zhang, X. (2013). A novel biomimetic analysis system for quantitative characterisation of sclerosing foams used for the treatment of varicose veins. Journal of Materials Science Materials in Medicine, 24(6), 1417-1423. DOI: 10.1007/s10856-013-4913-6

Carugo, D., ElMahdy, M., Zhao, X., Drake, M., Zhang, X., & Clavica, F. (2013). An artificial model for studying fluid dynamics in the obstructed and stented ureter. Proc. IEEE Engineering in Medicine and Biology Conference (EMBC), 5335-5338. DOI: 10.1109/EMBC.2013.6610754

Zhang, X. (2013). Editorial (Mini hot-topic: Bioanalysis in microscale bioengineering). Current Analytical Chemistry, 9(1), 1-1. DOI: 10.2174/157341113804486491

Rmaile, A., Carugo, D., Capretto, L., Zhang, X., Wharton, J. A., Thurner, P. J., ... Stoodley, P. (2013). Microbial tribology and disruption of dental plaque bacterial biofilms. Wear, 306(1-2), 276-284. DOI: 10.1016/j.wear.2013.02.010

Capretto, L., Carugo, D., Mazzitelli, S., Nastruzzi, C., & Zhang, X. (2013). Microfluidic and lab-on-a-chip preparation routes for organic nanoparticles and vesicular systems for nanomedicine applications. Advanced Drug Delivery Reviews, 65(11-12), 1496-1532. DOI: 10.1016/j.addr.2013.08.002

Carboni, M., Capretto, L., Carugo, D., Stulz, E., & Zhang, X. (2013). Microfluidic-based continuous flow formation of triangular silver nanoprisms with tunable surface plasmon resonance. Journal of Materials Chemistry C, 1(45), 7540-7546. DOI: 10.1039/C3TC31335B

Capretto, L., Mazzitelli, S., Colombo, G., Piva, R., Penolazzi, L., Vecchiatini, R., ... Nastruzzi, C. (2013). Production of polymeric micelles by microfluidic technology for combined drug delivery: application to osteogenic differentiation of human periodontal ligament mesenchymal stem cells (hPDLSCs). International Journal of Pharmaceutics, 440(2), 195-206. DOI: 10.1016/j.ijpharm.2012.07.057

Ankrett, D. N., Carugo, D., Lei, J., Glynne-Jones, P., Townsend, P. A., Zhang, X., & Hill, M. (2013). The effect of ultrasound-related stimuli on cell viability in microfluidic channels. Journal of Nanobiotechnology, 11(20), 1-5. DOI: 10.1186/1477-3155-11-20

Carugo, D., Capretto, L., Willis, S., Lewis, A. L., Grey, D., Hill, M., & Zhang, X. (2012). A microfluidic device for the characterisation of embolisation with polyvinyl alcohol beads through biomimetic bifurcations. Biomedical Microdevices, 14(1), 153-163. DOI: 10.1007/s10544-011-9593-8

Capretto, L., Cheng, W., Carugo, D., Katsamenis, O. L., Hill, M., & Zhang, X. (2012). Mechanism of co-nanoprecipitation of organic actives and block copolymers in a microfluidic environment. Nanotechnology, 23(37), 375602. DOI: 10.1088/0957-4484/23/37/375602

Capretto, L., Mazzitelli, S., Brognara, E., Lampronti, I., Carugo, D., Hill, M., ... Nastruzzi, C. (2012). Mithramycin encapsulated in polymeric micelles by microfluidic technology as novel therapeutic protocol for beta-thalassemia. International Journal of Nanomedicine, 2012:7, 307-324. DOI: 10.2147/IJN.S25657

Das, T., Carugo, D., Zhang, X., & Chakraborty, S. (2012). Oscillation dynamics of embolic microspheres in flows with red blood cell suspensions. Journal of Applied Physics, 112(12), 124701-[7pp]. DOI: 10.1063/1.4768889

Tang, X., Nan, Y., Huang, F., & Zhang, X. (2012). Oscillations of methane oxidation over metallic nickel surfaces. Reaction Kinetics, Mechanisms and Catalysis, 107(1), 245-252. DOI: 10.1007/s11144-012-0461-1

Capretto, L., Carugo, D., Cheng, W., Hill, M., & Zhang, X. (2011). Continuous-flow production of polymeric micelles in microreactors: experimental and computational analysis. Journal of Colloid and Interface Science, 357(1), 243-251. DOI: 10.1016/j.jcis.2011.01.085

Carugo, D., Ankrett, D. N., Glynne-Jones, P., Capretto, L., Boltryk, R. J., Zhang, X., ... Hill, M. (2011). Contrast agent-free sonoporation: the use of an ultrasonic standing wave microfluidic system for the delivery of pharmaceutical agents. Biomicrofluidics, 5(4), 044108-[15pp]. DOI: 10.1063/1.3660352

Mazzitelli, S., Capretto, L., Carugo, D., Zhang, X., Piva, R., & Nastruzzi, C. (2011). Optimised production of multifunctional microfibres by microfluidic chip technology for tissue engineering applications. Lab on a Chip, 11, 1776-1785. DOI: 10.1039/c1lc20082h

Atkin, S. L., Barrier, S., Cui, Z., Fletcher, P. D. I., Mackenzie, G., Panel, V., ... Zhang, X. (2011). UV and visible light screening by individual sporopollenin exines derived from Lycopodium clavatum (club moss) and Ambrosia trifida (giant ragweed). Journal of Photochemistry and Photobiology B: Biology, 102(3), 209-217. DOI: 10.1016/j.jphotobiol.2010.12.005

Li, M-F., Fan, Y-M., Xu, F., Sun, R-C., & Zhang, X-L. (2010). Cold sodium hydroxide/urea based pretreatment of bamboo for bioethanol production: characterization of the cellulose rich fraction. Industrial Crops and Products, 32(3), 551-559. DOI: 10.1016/j.indcrop.2010.07.004

Capretto, L., Cheng, W., Carugo, D., Hill, M., & Zhang, X. (2010). Microfluidic reactors for controlled synthesis of polymeric micelles. Journal of Controlled Release, 148(1), e25-e26. DOI: 10.1016/j.jconrel.2010.07.037

Anderson, K., Cooper, J. M., Haswell, S. J., Marshall, D., Yin, H., & Zhang, X. (2010). Microfluidic-based measurements of cytochrome P450 enzyme activity of primary mammalian hepatocytes. Analyst, 135, 1282-1287. DOI: 10.1039/c0an00031k

Mazzitelli, S., Capretto, L., Zhang, X. L., Penolazzi, L., Lambertini, E., Piva, R., & Nastruzzi, C. (2010). Process optimization for the production of alginate microparticles containing wjmscs by a design of experiments (doe) approach. Journal of Controlled Release, 148(1), e76-e77. DOI: 10.1016/j.jconrel.2010.07.014

Capretto, L., Focaroli, S., Zhang, X. L., Mazzitelli, S., & Nastruzzi, C. (2010). Production of low cost microfluidic chips by a “shrinking” approach: applications to emulsion and microparticle production. Journal of Controlled Release, 148(1), e26-e28. DOI: 10.1016/j.jconrel.2010.07.038

Ni, B. H., Lee, C., Sun, R. C., & Zhang, X. L. (2009). Microwave assisted heterogeneous catalysis: effects of varying oxygen concentrations on the oxidative coupling of methane. Reaction Kinetics and Catalysis Letters, 98(2), 287-302. DOI: 10.1007/s11144-009-0089-y

Zhang, X., Coupland, P., Fletcher, P. D. I., & Haswell, S. J. (2009). Monitoring of liquid flow through microtubes using a micropressure sensor. Chemical Engineering Research and Design, 87(1), 19-24. DOI: 10.1016/j.cherd.2008.06.007

Ren, J. L., Peng, F., Sun, R. C., & Zhang, X. L. (2009). Preparation and characterization of carbamoylethyl hemicelluloses. e-Polymers, 2009(3), 1-11.

Zhang, X., Jones, P., & Haswell, S. J. (2008). Attachment and detachment of living cells on modified microchannel surfaces in a microfluidic-based lab-on-a-chip system. [In IMRET9 Special Issue: Microreaction Technology IMRET 9: Proceedings of the Ninth International Conference on Microreaction Technology]. Chemical Engineering Journal, 135(Supplement 1), S82-S88. DOI: 10.1016/j.cej.2007.07.054

Zhang, X., Yin, H., Cooper, J. M., & Haswell, S. J. (2008). Characterization of cellular chemical dynamics using combined microfluidic and Raman techniques. Analytical and Bioanalytical Chemistry, 390(3), 833-840. DOI: 10.1007/s00216-007-1564-9

Yoon, T-H., Park, S-H., Min, K-I., Zhang, X., Haswell, S. J., & Kim, D-P. (2008). Novel inorganic polymer derived microreactors for organic microchemistry applications. Lab on a Chip, 8(9), 1454-1459. DOI: 10.1039/b804726j

Yin, H., Pattrick, N., Zhang, X., Klauke, N., Cordingley, H. C., Haswell, S. J., & Cooper, J. M. (2008). Quantitative comparison between microfluidic and microtiter plate formats for cell-based assays. Analytical Chemistry, 80(1), 179-185. DOI: 10.1021/ac701958z

Yin, H., Zhang, X., Pattrick, N., Klauke, N., Cordingley, H. C., Haswell, S. J., & Cooper, J. M. (2007). Influence of hydrodynamic conditions on quantitative cellular assays in microfluidic systems. Analytical Chemistry, 79(18), 7139-7144. DOI: 10.1021/ac071146k

Zhang, X., Yin, H., Cooper, J. M., & Haswell, S. J. (2006). A microfluidic based system for analysis of single cells based on Ca2+ flux. Electrophoresis, 27(24), 5093-5100. DOI: 10.1002/elps.200600390

Zhang, X., & Hayward, D. O. (2006). Applications of microwave dielectric heating in environment-related heterogeneous gas-phase catalytic systems. Inorganica Chimica Acta, 359(11), 3421-3433. DOI: 10.1016/j.ica.2006.01.037

Zhang, X., Cooper, J. M., Monaghan, P. B., & Haswell, S. J. (2006). Continuous flow separation of particles within an asymmetric microfluidic device. Lab on a Chip, 6(4), 561-566. DOI: 10.1039/b515272k

Zhang, X., & Haswell, S. J. (2006). Materials matter in microfluidic devices. MRS Bulletin, 31, 95-99.

Zhang, X., Wiles, C., Painter, S. L., & Haswell, S. J. (2006). Microreactors as tools for chemical research. Chimica Oggi/Chemistry Today, 24, 43-45.

Arslan, G., Özmen, M., Gündüz, B., Zhang, X., & Ersöz, M. (2006). Surface modification of glass beads with an aminosilane monolayer. Turkish Journal of Chemistry, 30(2), 203-210.

Zhang, X., Lee, C. S-M., Hayward, D. O., & Mingos, D. M. P. (2005). Oscillatory behaviour observed in the rate of oxidation of methane over metal catalysts. [In special issue: Oscillatory Behaviour of Heterogeneous Catalytic Reactions]. Catalysis Today, 105(2), 283-294. DOI: 10.1016/j.cattod.2005.02.040

Broadwell, I., Fletcher, P. D. I., Haswell, S. J., Zhang, X., Allen, R. W. K., MacInnes, J. M., & Du, X. (2004). Pressure-driven and electroosmotic flows and electrical currents in Lab-on-a-Chip micro reactor devices. Trends in Physical Chemistry, 10, 117-133.

Zhang, X., Lee, C., Mingos, D. M. P., & Hayward, D. O. (2003). Carbon dioxide reforming of methane with Pt catalysts using microwave dielectric heating. Catalysis Letters, 88(3-4), 129-139. DOI: 10.1023/A:1024049403422

Zhang, X., Hayward, D. O., & Mingos, D. M. P. (2003). Effects of microwave dielectric heating on heterogeneous catalysis. Catalysis Letters, 88(1-2), 33-38. DOI: 10.1023/A:1023530715368

Zhang, X., Hayward, D. O., & Mingos, D. M. P. (2003). Further studies on oscillations over nickel wires during the partial oxidation of methane. Catalysis Letters, 86(4), 235-243. DOI: 10.1023/A:1022672219909

Fletcher, P. D. I., Haswell, S. J., & Zhang, X. (2003). Monitoring of chemical reactions within microreactors using an inverted Raman microscopic spectrometer. [In special issue: Proceedings of the APCE 2002 Meeting Shanghai, China, October 11-14, 2002]. Electrophoresis, 24(18), 3239-3245. DOI: 10.1002/elps.200305532

Zhang, X., Lee, C., Mingos, D. M. P., & Hayward, D. O. (2003). Oscillatory behaviour during the partial oxidation of methane over cobalt wires and foils. Applied Catalysis A: General, 248(1-2), 129-142. DOI: 10.1016/S0926-860X(03)00154-6

Zhang, X., Lee, C., Mingos, D. M. P., & Hayward, D. O. (2003). Oxidative coupling of methane using microwave dielectric heating. Applied Catalysis A: General, 249(1), 151-164. DOI: 10.1016/S0926-860X(03)00188-1

Zhang, X., Hayward, D. O., & Mingos, D. M. P. (2002). Dielectric properties of MoS2 and Pt catalysts: effects of temperature and microwave frequency. Catalysis Letters, 84(3-4), 225-233. DOI: 10.1023/A:1021488222243

Fletcher, P. D. I., Haswell, S. J., & Zhang, X. (2002). Electrokinetic control of a chemical reaction in a lab-on-a-chip micro-reactor: measurement and quantitative modelling. Lab on a Chip, 2, 102-112. DOI: 10.1039/b201685k

Fletcher, P. D. I., Haswell, S. J., Pombo-Villar, E., Warrington, B. H., Watts, P., Wong, S. Y. F., & Zhang, X. (2002). Micro reactors: principles and applications in organic synthesis. Tetrahedron, 58(24), 4735-4757. DOI: 10.1016/S0040-4020(02)00432-5

Zhang, X., Hayward, D. O., & Mingos, D. M. P. (2002). Oscillatory behaviour during the partial oxidation of methane over nickel foils. Catalysis Letters, 83(3-4), 149-155. DOI: 10.1023/A:1021069510797

Fletcher, P. D. I., Haswell, S. J., & Zhang, X. (2001). Electrical currents and liquid flow rates in micro-reactors. Lab on a Chip, 1(2), 115-121. DOI: 10.1039/b106339c

Zhang, X., Hayward, D. O., Lee, C., & Mingos, D. M. P. (2001). Microwave assisted catalytic reduction of sulfur dioxide with methane over MoS2 catalysts. Applied Catalysis B: Environmental, 33(2), 137-148. DOI: 10.1016/S0926-3373(01)00171-0

Zhang, X., Hayward, D. O., & Mingos, D. M. P. (2001). Microwave dielectric heating behaviour of supported MoS2 and Pt catalysts. Industrial and Engineering Chemistry Research, 40(13), 2810-2817. DOI: 10.1021/ie0007825

Broadwell, I., Fletcher, P. D. I., Haswell, S. J., McCreedy, T., & Zhang, X. (2001). Quantitative 3-dimensional profiling of channel networks within transparent 'lab-on-a-chip' microreactors using a digital imaging method. Lab on a Chip, 1(1), 66-71. DOI: 10.1039/b103280c

Zhang, X., Mingos, D. M. P., & Hayward, D. O. (2001). Rate oscillations during partial oxidation of methane over chromel–alumel thermocouples. Catalysis Letters, 72(3-4), 147-152. DOI: 10.1023/A:1009036128275

Zhang, X., Hayward, D. O., & Mingos, D. M. P. (1999). Apparent equilibrium shifts and hot-spot formation for catalytic reactions induced by microwave dielectric heating. Chemical Communications, (11), 975-976. DOI: 10.1039/a901245a

Book Chapters

Capretto, L., Cheng, W., Hill, M., & Zhang, X. (2011). Micromixing within microfluidic devices. In Topics in Current Chemistry. (pp. 1-42). London, GB: Springer. DOI: 10.1007/128_2011_150

Cheng, W., Capretto, L., Hill, M., & Zhang, X. (2011). Organic nanoparticles using microfluidic technology for drug-delivery applications. In C. S. S. R. Kumar (Ed.), Polymeric Nanomaterials. (pp. 221-257). (Nanomaterials for the Life Sciences). Weinheim, DE: Wiley.

Zhang, X., Mingos, M., & Hayward, D. (2008). Microwave assisted heterogeneous catalysis. In D. Marmaduke (Ed.), Progress in Heterogeneous Catalysis. USA: Nova Science Publishers.

Fletcher, P. D. I., Haswell, S. J., Watts, P., & Zhang, X. (2004). Lab-on-a-Chip micro reactors for chemical synthesis. In J. A. Schwarz, C. Contescu, & K. Putyera (Eds.), Encyclopedia of Nanoscience and Nanotechnology. (pp. 1547-1564). New York, USA: Marcel Dekker.

Conferences

Carugo, D., Ankrett, D. N., Glynne-Jones, P., Capretto, L., Boltryk, R. J., Townsend, P. A., ... Hill, M. (2011). Contrast agent-free cell sonoporation using a continuous-flow microfluidic device. Paper presented at The 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS ), United States.

Grigorov, A. V., Hua, P., & Zhang, X. (2010). Fabrication and optimization of silver electrode porous membrane microfluidic devices for electrokinetic energy harvesting applications. Paper presented at The 17th Joint Annual Conference of CSCST & SCS CS, United Kingdom.

Patents

Haswell, S. J., Fletcher, P. D. I., & Zhang, X. (2006). Method to monitor chemical reactions in a micro-reactor by measuring an electrical current Patent No. US6989090.

Haswell, S. J., Fletcher, P. D. I., & Zhang, X. (2003). Depth and concentration estimation Patent No. EP1271129.

Haswell, S. J., Fletcher, P. D. I., & Zhang, X. (2003). Monitoring of chemical reactions in a micro-reactor Patent No. EP1283071.

Haswell, S. J., Fletcher, P. D. I., & Zhang, X. (2001). Optical measurement of the dimension of an opening inside a micro-reactor body and the concentration of the fluid therein Patent No. GB2378242.

Module title	Module code	Discipline	Role
Engineering Design	SESM3001	Mechanical	Course leader

Dr Xunli Zhang
Engineering and the Environment University of Southampton Highfield Southampton SO17 1BJ

Room Number:7/4071

Telephone:(023) 8059 5099
Email:XL.Zhang@soton.ac.uk

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