The IfLS has run a sponsored PhD programme since 2012/13. Funding is offered in open competition to interdisciplinary research teams based at Southampton and high-quality projects are selected. IfLS-sponsored interdisciplinary projects, students and supervisors are set out below.
Machine learning of clinical outcomes from time-series and imaging data | Prof Niranjan (FEPS), Prof Ben MacArthur (FSS) with University Hospital Southampton NHS FT | Alex Thomas |
Network modelling of structural and functional brain connectivity in new-borns | Dr Ruben Sanchez-Garcia (FSS), Prof Ben MacArthur, (FSS) Dr Brigitte Vollmer (FM), Dr Angela Darekar (UHS),Dr Finn Lennartsson (Lund University, Sweden) | Marshall Mitchell |
Machine Learning to improve multidisciplinary decision-making in the assessment and management of Oesophageal adenocarcinoma | Prof Tim Underwood (FM), Prof Age Chapman (FEPS), Dr Ganesh Vigneswaran with University Hospital Southampton NHS FT | Navamayooran Thavanesan |
Understanding the molecular interaction between the γδ T-cell antigen receptor and its ligands; paving the way for future immunotherapy | Dr Salah Mansour (FM), Dr Ivo Tews (FELS) | Danny Burns |
Microbes and the ageing brain: do host-microbe interactions accelerate age-related cognitive decline? (SoCoBio DTP studentship) | Prof Jessica Teeling (FELS) with SoCoBio DTP partners | Laura Freeman |
Analysing the functional significance of a primate-specific non-canonical glutamate receptor (SoCoBio DTP studentship) | Dr Mariana Vargas-Caballero (FELS), Dr Katrin Deinhardt (FELS), with SoCoBio DTP partners | Steven Houghton |
Resistance is futile: hijacking bacterial signal transductin pathways to increase antibiotic uptake | Dr Seung Lee (FEPS), Dr Nick Evans (FEPS), Dr Tracey Newman (FM) | Kirsty Teahan |
Impact of obesity on human and murine dermal lymphatics | Dr Jaswinder Sethi (FM), Dr Peter Worsley (FELS) | Maria Kousetti |
Exploring novel electrophilic chemical warheads in Targeted Covalent Inhibition | Dr Matthias Baud (FEPS), Prof Graham Packham, Dr Andrew Steele (FM) | Ruxandra Moraru |
Metabolic reprogramming of NK cells in hepatocellular carcinoma | Prof Salim Khakoo (FM), Prof Marcel Utz (FEPS) | Evie Rogers |
Improving diagnosis of genetic disease through computational investigation of splicing | Prof Diana Baralle (FM), Prof Niranjan (FEPS), Dr Jenny Lord (FM) | Ron Strauch |
Stitched beta sheets as chemical probes of protein-protein interaction networks | Dr Sam Thompson (FEPS), Dr Rob Ewing (FELS), Dr Paul Skipp (FELS) | Rose Bannister |
Boozy bacteria: A combined experimental and computational characterisation of the effect of alcohol on bacterial membranes | Prof Syma Khalid (FEPS), Dr Phil Williamson (FELS) | Callum Waller |
Development of a Core Outcome Set (COS) and identification of measurement tools for Prosthetic Rehabilitation following lower limb amputation | Dr Maggie Donovan-Hall (FELS), Dr Alex Dickinson (FEPS), Dr Cheryl Metcalf (FELS) | Chantel Ostler |
A Description of new baryonychine (Theropoda: Spinosauridae) material and assessment of trigeminal (palaeo) neuroanatomy in extinct and extant archosaurs | Dr Neil Gostling, Dr Claire Clarkin, Dr Philip Schneider | Chris Barker |
Exploring the dynamic contribution of asymmetric cell divisions to the identity and function of mammary stem cells using genetic lineage tracing in vivo and mathematical modelling |
Dr Salah Elias (FELS), Dr Philip Greulich (FSS), Prof Ben MacArthur (FSS) | Camilla Nightingale |
Integration of health informatics: ‘big data’ for clinical translation in paediatric inflammatory bowel disease | Prof Sarah Ennis (FM), Prof Ben MacArthur (FSS), Dr Enrico Mossotto (FM), Prof Mark Beattie (UHS) | Imogen Stafford |
Protein NMR On A Chip | Dr Joern Werner (FELS), Prof Marcel Utz (FEPS) | Marek Plata |
Identifying complex genetic oscillators from single cell data | Dr Ruben Sanchez-Garcia (FSS), Prof Ben MacArthur (FSS) | Michael Casey |
Plant-Microbe interactions in a changing climate | Dr Bjorn Robroek (FELS), Prof Pete Langdon(FELS), Prof Paul Hughes (FELS) | Magdalena Steele |
Recovery of neuronal function and memory in a mouse model of hemorrhagic stroke and first steps in translation of findings from mouse to human. | Dr Mariana Vargas-Caballero (FELS), Dr Ian Galea (FM), Diederik Bulters (UHS) | Hannah Warming |
How does autophagy regulate the development of idiopathic pulmonary fibrosis (IPF)? | Dr Yihua Wang (FELS), Prof Donna Davies (FM), Dr Rob Ewing (FELS), Dr Mark Glynne Jones (FM) | Yilu Zhou |
Development and application of powerful methods for identifying selective sweeps in human and chicken genomes | Prof Andrew Collins (FM), Prof Tim Sluckin (FSS), Dr Reuben Pengelly (FM), Prof Sarah Ennis (FM) | Clare Horscroft |
Modulating mechanobiology and blood supply to improve bone strength in Paget’s disease. | Dr Claire Clarkin (FELS), Dr Bram Sengers (FEPS), Dr Philipp Schneider (FEPS) | Alisha Sharma |
Digital histopathology resource for image-based diagnosis | Dr Philipp Schneider (FEPS), Dr Peter Lackie (FM), Dr Jane Warner (FM), Dr Katsamenis, Dr Mark Jones, Prof Ian Sinclair (FEPS) | Elaine Ho |
Physician and Surgeon Down A Tube: Advanced Optical Fibre Guided Diagnosis and Surgery | Prof Sumeet Mahajan (FEPS), Prof Francesco Poletti (FEPS), Mr Diederik Bulters (UHS) | Marzanna Szwaj |
Acoustic nanobubbles for mechanostimulation and drug delivery in fracture repair | Dr Nick Evans (FM), Dr Dario Carugo (FEPS), Dr Tracey Newman (FM) | Sara Ferri |
Automated Analysis of Lung Sounds as a Predictor of Ventilator Associated Pneumonia (VAP) | Prof Anna Barney (FEPS), Prof Anne Bruton (FELS), Prof Mike Grocott (FM) | Ravi Pal |
Inferring early warning signals of ecosystem collapse at the end of the Eocene greenhouse | Dr Thomas Ezard (FELS), Dr Sandra Nogue-Bosch (FELS), Dr Steven Bohaty (FELS) | Lorna Kearns |
Control of stem cell fate and clonal dynamics | Dr Philip Greulich (FSS), Prof Ben MacArthur (FSS) | Cristina Parigini |
Unravelling the clonal nature of microglial diversity in the brain. | Dr Diego Gomez Nicola (FELS), Dr Matt Rose-Zerilli (FM), Dr Jonathan West (FM) | Tim Muntslag |