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Doctor Tim Fenton

Dr Tim Fenton

Associate Professor in Cancer Biology

Accepting applications from PhD students.

Connect with Tim


Address: Southampton General Hospital, Tremona Road Shirley, SO16 6YD (View in Google Maps)


Tim’s research interests are focused on understanding the molecular changes that occur as cancers develop and evade destruction by our immune system. His goal is to apply these findings to enable earlier diagnosis and more effective therapy.

Tim’s group has made several important contributions, including the discovery that APOBEC enzymes (part of our innate immune response to viral infection) cause oncogenic driver mutations, thus directly contributing to cancer development. His group also helped to clarify the role of human papillomavirus infection in head and neck cancer causation and prognosis and developed a computational tool (MethylCIBERSORT), to allow estimation of the different cell types present in the tumour microenvironment using DNA methylation data from bulk tumour samples.

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