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The University of Southampton
Health Sciences
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Dr Chloe Grimmett PhD, BSc hons

NIHR post-doctoral fellow and Senior Research Fellow for the Macmillan Survivorship Research Group

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Dr Chloe Grimmett is a National Institute of Health Research (NIHR) Post-Doctoral Research Fellow and Senior Research Fellow for Macmillan Survivorship Research Group, Health Sciences. Chloe’s research interests include the development of interventions to support self-management following a cancer diagnosis. She has a particular interest in the role of physical activity as a component of prehabilitation as well as during recovery from cancer treatment.

I’ve seen the physical and mental health benefits people affected by cancer can experience by being physically active. I want to find the best way to support individuals to be active for the long term, preparing for treatment, aiding recovery and maximising their quality of life and wellbeing.

Chloe joined the Macmillan Survivorship Research Group (MSRG) from University College London in 2012 where she now works as a Senior Research Fellow supporting the MSRG’s programme of work, dedicated to understanding patterns of recovery after cancer diagnosis and treatment and supporting the self-management of cancer related problems.

Chloe holds an NIHR post-doctoral fellowship which aims to better understand the mechanisms that determine sustained habitual physical activity in people following a cancer diagnosis. She plans to use this to design an intervention to enable cancer survivors to be physical activity in the long term and that can be integrated into current health care and community services.

Chloe also has research interest in psychological and physical optimisation of patients prior to cancer surgery and is the lead behavioural scientist for the Wessex Fit for Cancer Surgery (WesFit) trial. This trial, funded by NHS England Transformation Funding in collaboration with the Wessex Cancer Alliance, explores the impact of physical and psychological prehabilitation prior to cancer surgery. Chloe is also a member of the National Cancer Research Institute Clinical Acute Care and Toxicities Workstream, the NIHR Cancer and Nutrition Collaboration and the International Moving Through Cancer Taskforce.


Research interests

My research interests focus on the development and evaluation of interventions that support the physical and psychological wellbeing of people affected by cancer prior to cancer treatment (prehabilitation) and during recovery.

Current projects include

SafeFit: Virtual clinics to deliver universal interventions to maintain and improve physical and psychological wellbeing in people affected by cancer who are following social distancing guidance: A COVID-19 targeted Trial

WesFit: The Wessex Fit-4-Cancer Surgery Trial: a factorial design, pragmatic randomised controlled trial investigating the effects of a multi-modal prehabilitation programme in patients undergoing elective major intra-cavity cancer surgery.

NIHR post-doctoral fellowship: development of a conceptual model and intervention to promote sustained, long-term physical activity after cancer

CanGene-CanVar: CRUK Population Science Accelerator award. Data resources, clinical and education tools to leverage cancer susceptibility genetics for early detection and prevention of cance.

PhD supervision

Student: Amy Din
Supervisors: Claire Foster and Chloe Grimmett
Facilitating the promotion of healthful behaviour change by healthcare professions to colorectal cancer survivors

Student: Peter Paterson
Supervisors: Denny Levett and Chloe Grimmett
Psychological responses of people affected by cancer who are invited to take part in prehabilitation programmes.

Student: Kelly Kohut
Supervisors: Diana Eccles, Claire Foster and Chloe Grimmett

CanGene-CanVar CRUK studentship

Research group

Cancer & Life Limiting Conditions

Research theme(s)

Active Living

Health Needs


Research project(s)

Macmillan Survivorship Research Group - 5 year research programme

MOTH Project 1: Maintaining physical activity through the use of digital interventions for people with a long-term condition/s (LTCs): A scoping review

This scoping review aims to explore the range of available literature on digital tools to support the maintenance of physical activity for people with LTCs. This review will identify the theoretical underpinnings of these interventions and the experiences, barriers and facilitators of those using them.

Member of:

  • National Cancer Research Institute Acute Care (NCRI) and Toxicities working group.
  • National Institute for Health Research (NIHR) Cancer and Nutrition Collaboration
  • International Moving Through Cancer Taskforce
  • Cancer Prehabilitation Consortium
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Dr Chloe Grimmett
Health Sciences, University of Southampton, Highfield, Southampton SO17 1BJ

Room Number : 67/4053

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