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The University of Southampton
Medicine
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J.Sethi@soton.ac.uk

Dr Jaswinder K Sethi BSc(Hons), DPhil(Oxon), FRSB

Principal Research Fellow in Immunometabolism, Welcome Trust Career Re-entry Fellow,Honorary NHS-Trust Research Fellow

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Dr Jaswinder K. Sethi is a Principal Research Fellow in Immunometabolism, a Wellcome Trust Career Re-entry Fellow and an honorary NHS Research Fellow based in the Faculty of Medicine at the University of Southampton

Dissecting how tissues sense, translate, and integrate nutritional cues is key to understanding healthy development and finding new therapeutic targets for treating obesity-linked metabolic diseases

Biography

Educated in London and graduated with first-class honours in biological sciences from Birkbeck College, University of London. This part-time degree was completed whilst maintaining a full-time technical research post at University College London. It also planted the seeds and mechanistic interests in cell communication. This led to a DPhil in calcium signalling from Oxford University, followed by postdoctoral training at Harvard University. Here she performed pioneering studies on molecular mechanisms linking obesity and insulin resistance with Gokhan Hotamisligil that catalysed the birth of a new field of research: Immunometabolism. Returning to the UK in 2000, Dr Sethi set up an independent research group at University of Cambridge to investigate Immunometabolic Signalling in Tissue Remodelling and Metabolic Disease. In 2017, the Sethi laboratory relocated to the University of Southampton and University Hospital Southampton NHS Foundation Trust.

Expertise: Immunometabolism, Cellular Signalling, Adipose Tissue Development & Biology, Tissue Remodelling, Metabolic Syndrome, Obesity, Type 2 Diabetes, Fatty Liver Disease, Cardiovascular Disease, Cancer

For more information see Dr Sethi’s Lab website at immunometab.com.
Follow our Lab's latest news on Twitter @SethiLab.

Qualifications

BSc (Hons), Biological Sciences, Birkbeck College - University of London, 1993
DPhil (Oxon), Physiological Sciences, University of Oxford, 1997

Appointments held

Research Technician, Department of Medicine, University College London, 1989 – 1993

MRC PhD/DPhil Scholar, Department of Pharmacology, Oxford University, 1993 – 1996

US-UK Fulbright Scholar, Department of Nutrition, Harvard University, 1997

Wellcome Trust Prize Postdoctoral Travelling Fellow (Outgoing), Department of Nutrition, Harvard University, 1997 - 1999

Wellcome Trust Prize Postdoctoral Travelling Fellow (Returning), Department of Clinical Biochemistry, University of Cambridge, 2000 - 2001

Diabetes UK RD Lawrence Fellow, Department of Clinical Biochemistry, University of Cambridge, 2001

BBSRC David Phillips Research Fellow, Department of Clinical Biochemistry, University of Cambridge, 2002 – 2006

Senior Teaching Scholar in Medicine Trinity Hall, University of Cambridge, 
2004 – 2009

Honorary Researcher in Metabolic Medicine, Cambridge University Hospitals & NHS Trust, 2006 - 2014

Principal Investigator & Group Leader, Institute of Metabolic Science – Metabolic Research Laboratories, University of Cambridge, 2007-2014

Visiting Professor, Dept. Scienza Del Farmaco, Università del Piemonte Orientale, Novara, Italy, 2014

PhD supervision

Ranmali Nawaratne PhD (Cantab), (-2004)
William P. Cawthorn PhD (Cantab), (-2009)
Meghana N. Patel PhD (Cantab), (-2012)
TBA (Soton), (2018)

2018/2019 PhD Studentship

Title: Role of adipose tissue function in fatty liver disease
Supervisors: Dr J.K. Sethi, Prof C.D. Byrne and Prof P.C. Calder
Funding: NIHR Southampton Biomedical Research

Editorial Board Membership

Biochemical Journal, Portland Press (2006-2016)
Cell Biochemistry & Function, Wiley & Sons Ltd, (2007-2013)
International Journal of Obesity, NPG (2010-2016, 2016-date)
PLoS ONE, Public Library of Science (2010 - date)
Adipocyte, Taylor & Francis (Founding EB member, 2012-date)
iScience, Cell Press (Founding EB member, 2018 – date)

Funding Panel Membership

L'Agence nationale de la recherche (ANR), France (2013-2015)
Biotechnology and biological Sciences Research Council (BBSRC), UK (2016-date)

Other Professional Membership

Fellow of the Royal Society of Biology

MEDI6108 Modern Management of Diabetes, Nutrition and Pharmacology (MODNAP): Deputy module lead
BMedSci: Personal Academic Tutor
BM5: Supervisor of laboratory projects
PhD/MSc: Supervisor

Come work with us!

We are keen to share our enthusiasm for problem solving and biomedical discovery through lab-based research. In addition to advertised posts, we are open to applications from potential visiting researchers or postdoctoral fellows. Please contact Dr J. K. Sethi for more details.

Dr Jaswinder K Sethi
Faculty of Medicine, University of Southampton, Building 85, Life Sciences Building, Highfield Campus, Southampton, SO171BJ

Room Number: SGH/IDS/MP887


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