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The University of Southampton
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Dr Jane Gibson BSc, MSc, PhD

Lecturer in Cancer Bioinformatics and Genomics

Dr Jane Gibson's photo

Dr Jane Gibson is a Lecturer in Cancer Bioinformatics and Genomics within Medicine at the University of Southampton.

Career History

2019-present: Lecturer in Cancer Bioinformatics and Genomics. Cancer Sciences, Faculty of Medicine, University of Southampton, UK.
2013-2019: Lecturer in Bioinformatics. Biological Sciences, University of Southampton, UK.
2012-2013: Career track award Fellow. Faculty of Medicine, University of Southampton, UK.
2008-2012: Postdoctoral research assistant. School of Medicine, University of Southampton, UK.
2002-2008: Research assistant. School of Medicine, University of Southampton, UK.

Academic Qualifications

2015: PGCAP (Merit) Postgraduate certificate in Academic Practice. University of Southampton, UK.
2008: PhD Genetic Epidemiology and Bioinformatics. University of Southampton, UK.
2002: MSc Biosystems and Informatics.  University of Liverpool, UK.
2001: BSc (Hons) Genetics.  University of Leeds, UK.

Research interests

My research involves statistical genetics and bioinformatics approaches to understanding the human genome and the changes which can lead to disease. Research areas include:

  • Studies which aim to determine genes underlying ophthalmic traits such as Age-related Macular Degeneration, Primary Open Angle Glaucoma and Nystagmus. This involves next generation sequencing and genetic association studies and (with Andrew Lotery, Jay Self & Sarah Ennis, Faculty of Medicine).
  • Analysis of tumour samples to determine somatic variants from exome and targeted gene sequencing approaches in cancer patients (with Jon Strefford, Faculty of Medicine).
  • The determination and characterisation of linkage disequilibrium patterns and homozygous regions in disease and population studies.
  • The development of in-house tools and software pipelines to enable streamlined bioinformatic analyses of next generation sequencing data.
  • Identifying genes causing Mendelian diseases and detection of susceptibility genes involved in familial cancers using exome sequencing (with colleagues at Wessex Clinical Genetics Service).
  • Analysis of genomic and transcriptomic data investigating domestciation of crop species (with Mark Chapman, BioSci)

Research group

Cancer Sciences

Affiliate research groups

Genomics, Epigenomics and Bioinformatics Research Theme, Computational and Systems Biology

PhD Supervision

Roshan Sood (2014-2018)
Project Title: Interpreting large-scale next generation sequence data using bioinformatic approaches.
Funding: Mayflower studentship

Luke O’Gorman (2015-2018) Co-Supervisor
Project Title: The Development of Bioinformatic Pipelines for Ophthalmic Disease
Funding: Gift of sight studentship

Gaia Andreoletti (Awarded 2016) Co-supervisor
Project Title: Genomic analyses of paediatric inflammatory bowel disease
Funding: Kerkut Trust and CICRA studentships

Reuben Pengelly (Awarded 2015) Co-supervisor
Project Title: Genomic data analysis: populations, patients and pipelines
Funding: Faculty of Medicine doctoral training award and donation

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Dr Gibson contributes to teaching in BSc Biomedical Science, Biochemistry and Pharmacology, delivering lectures and workshops on Bioinformatics (BIOL2013, BIOL3063/6074/6055).

She also supervises undergraduate and postgraduate research projects (BIOL3069, BIOL6013, MEDI3048).

Dr Gibson lectures on the MSc in Genomic Medicine (MEDI6215), and has previously contributed to the BM5 programme, delivering lectures and facilitating tutorials, and also takes on the role of Personal Tutor.

Dr Jane Gibson
Faculty of Medicine, University of Southampton, Building 85, Life Sciences Building, Highfield Campus, Southampton, SO171BJ

Room Number: SGH/CS/C15/MP824

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