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Research project

Prof R. Read: MRC Experimental Human Challenge with Genetically Modified Commensals to Investigate Respiratory Tract Mucosal Immunity and Colonisation

Staff

Lead researcher

Professor Robert Read

Chair of Infectious Diseases
Other researchers

Professor Ian Clarke

Professor of Virology

Research interests

  • Transposon mutagenesis of Chlamydia species
  • Cell culture systems and replicons for human noroviruses

Professor Saul Faust MBBS, FRCPCH, PhD, FHEA, OBE

Professor Paediatric Immunology & Infect

Research outputs

Effect of priming interval on reactogenicity, peak immunological response, and waning after homologous and heterologous COVID-19 vaccine schedules: exploratory analyses of Com-COV, a randomised control trial
Robert H. Shaw,
Xinxue Liu,
Arabella S.V. Stuart,
Melanie Greenland,
Parvinder K. Aley,
Nick J. Andrews,
,
,
Saul Faust,
& Robert Read
, 2022 , The Lancet Respiratory Medicine , 10 (11) , 1049--1060
DOI: 10.1016/S2213-2600(22)00163-1
Type: article
Immunogenicity, safety, and reactogenicity of heterologous COVID-19 primary vaccination incorporating mRNA, viral-vector, and protein-adjuvant vaccines in the UK (Com-COV2): a single-blind, randomised, phase 2, non-inferiority trial
Arabella S V Stuart,
Robert H Shaw,
Xinxue Liu,
Melanie Greenland,
Parvinder K Aley,
Nick J Andrews,
,
J C Cameron,
Sue Charlton,
Elizabeth A Clutterbuck,
Andrea M Collins,
Tom Darton,
Tanya Dinesh,
Christopher J A Duncan,
Anna England,
Saul N Faust,
Daniela M Ferreira,
Adam Finn,
Anna L Goodman,
Christopher A Green,
Bassam Hallis,
Paul T Heath,
Helen Hill,
Bryn M Horsington,
Teresa Lambe,
Rajeka Lazarus,
Vincenzo Libri,
Patrick J Lillie,
Yama F Mujadidi,
Ruth Payne,
Emma L Plested,
Samuel Provstgaard-Morys,
Maheshi N Ramasamy,
Mary Ramsay,
Robert C Read,
Hannah Robinson,
Gavin R Screaton,
Nisha Singh,
David P J Turner,
Paul J Turner,
Iason Vichos,
Rachel White,
Jonathan S Nguyen-Van-Tam,
& Matthew D Snape
, 2022 , The Lancet , 399 (10319) , 36--49
DOI: 10.1016/S0140-6736(21)02718-5
Type: article
Neisseria lactamica controlled human infection model
Adam P Dale,
Diane F Gbesemete,
Robert C Read,
& Jay R Laver
, 2022
DOI: 10.1007/978-1-0716-1900-1_21
Type: bookChapter
Safety and immunogenicity of seven COVID-19 vaccines as a third dose (booster) following two doses of ChAdOx1 nCov-19 or BNT162b2 in the UK (COV-BOOST): a blinded, multicentre, randomised, controlled, phase 2 trial
Alasdair P S Munro,
Leila Janani,
Victoria Cornelius,
Parvinder K Aley,
Gavin Babbage,
David Baxter,
et al.,
,
Marcin Bula,
Katrina Cathie,
Krishna Chatterjee,
Kate Dodd,
Yvanne Enever,
Karishma Gokani,
Anna L Goodman,
Christopher A Green,
Linda Harndahl,
John Haughney,
Alexander Hicks,
Agatha A van der Klaauw,
Jonathan Kwok,
Teresa Lambe,
Vincenzo Libri,
Martin J Llewelyn,
Alastair C McGregor,
Angela M Minassian,
Patrick Moore,
Mehmood Mughal,
Yama F Mujadidi,
Jennifer Murira,
Orod Osanlou,
Rostam Osanlou,
Daniel R Owens,
Mihaela Pacurar,
Adrian Palfreeman,
Daniel Pan,
Tommy Rampling,
Karen Regan,
Stephen Saich,
Jo Salkeld,
Dinesh Saralaya,
Sunil Sharma,
Ray Sheridan,
Ann Sturdy,
Emma C Thomson,
Shirley Todd,
Chris Twelves,
Robert C Read,
Sue Charlton,
Bassam Hallis,
Mary Ramsay,
Nick J. Andrews,
Jonathan Nguyen-Van-Tam,
Matthew D. Snape,
Xinxue Liu,
& Saul N Faust
, 2021 , The Lancet , 398 (10318) , 2258--2276
DOI: 10.1016/S0140-6736(21)02717-3
Type: article
Safety and immunogenicity of heterologous versus homologous prime-boost schedules with an adenoviral vectored and mRNA COVID-19 vaccine (Com-COV): a single-blind, randomised, non-inferiority trial
Xinxue Liu,
Robert H. Shaw,
Arabella S.V. Stuart,
Melanie Greenland,
Parvinder K. Aley,
Nick J. Andrews,
,
,
J. Claire Cameron,
Sue Charlton,
Elizabeth A. Clutterbuck,
Andrea M. Collins,
Tanya Dinesh,
Anna England,
Saul N. Faust,
Daniela M. Ferreira,
Adam Finn,
Christopher A. Green,
Bassam Hallis,
Paul T. Heath,
Helen Hill,
Teresa Lambe,
Rajeka Lazarus,
Vincenzo Libri,
Fei Long,
Yama F. Mujadidi,
Emma L. Plested,
Samuel Provstgaard-Morys,
Maheshi N. Ramasamy,
Mary Ramsay,
Robert C. Read,
Hannah Robinson,
Nisha Singh,
David P.J. Turner,
Paul J. Turner,
Laura L. Walker,
Rachel White,
Jonathan S. Nguyen-Van-Tam,
Matthew D. Snape,
Alasdair P.S. Munro,
Jazz Bartholomew,
Laura Presland,
Sarah Horswill,
Sarah Warren,
Sophie Varkonyi-Clifford,
Stephen Saich,
Kirsty Adams,
Marivic Ricamara,
Nicola Turner,
Nicole Y. Yee Ting,
Sarah Whittley,
& Hannah Sainsbury
, 2021 , The Lancet , 398 (10303) , 856--869
DOI: 10.1016/S0140-6736(21)01694-9
Type: article