Research group

Interdisciplinary Musculoskeletal Health

4 Stained femur cross sections

The University hosts a substantial interdisciplinary community of researchers working to transform musculoskeletal health across the life course.

About

With expertise in regenerative medicine, physiology, engineering, orthopaedics, prosthetics and orthotics, rehabilitation and assistive technologies, epidemiology and clinical trial design, we aim to improve lives by delivering improved treatments, increasing the speed to market of musculoskeletal-focused technology and training the next generation of scientists and engineers. 

The population across the globe is living longer, which brings a number of healthcare challenges, especially in musculoskeletal health. The burden of age-related disease and injury is rising rapidly, having a detrimental impact on people’s quality of life and increasing the costs of healthcare provision. Loss of muscle mass and function is the leading reason for loss of independence in later life, and causes impaired mobility, falls, fractures, physical disability, increased insulin resistance and associated co-morbidities, and mortality. The number of hip fractures is expected to rise to 6.3 million by 2050 and the number of diabetic lower limb amputations has now risen to 7,000 per year in the UK and over 70,000 in the USA. 

The University is working to meet these challenges by creating networks of experts working in interdisciplinary musculoskeletal health research to develop new technologies, interventions and practices that will have a positive effect on people’s lives:

  • FortisNet is an interdisciplinary research network of clinical, academic and industrial partners that aims to develop products and services to transform musculoskeletal health. Launched in 2016, we have fostered over 50 new collaborations with other universities from across the UK, the NHS and industry. We have developed courses with national partners to help innovators understand how to bring medical technologies to market, and through investment in interdisciplinary studentships we are working to dissolve discipline boundaries, to train a new generation of life scientists and engineers for the benefit of society.
  • MyAge (Muscle resilience across the life course: from cells to society) is one of eleven UK Ageing Networks, funded by the Biotechnology and Biological Sciences Research Council and Medical Research Council. Led by the Institute for Life Sciences, together with partners from Birmingham, Nottingham and Imperial, the network will guide the future of muscle resilience research through roadmap development and interdisciplinary collaboration.

Research highlights

Preventing the transmission of non-communicable disease risk between generations

Research from the Developmental Origins of Health and Disease Centre demonstrates how the diet and lifestyle choices of prospective parents and pregnant mothers can affect the long-term health of their children.

Using nanoclay gel to regrow, repair and replace damaged cells

Southampton researchers have developed an innovative medical clay that can be used to apply regenerative medicine to patients with musculoskeletal conditions.

People, projects and publications

People

Dr Jennifer Williams

Lecturer

Research interests

  • Responsible and trustworthy audio processing applied to a variety of domains and use-cases;
  • Audio AI safety in terms of usability, privacy, and security;
  • Ethical issues of trust for audio AI (deepfake detection, voice-related rights, and speaker a…

Accepting applications from PhD students

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Dr Jeremy Blaydes

Associate Professor

Research interests

  • Transcriptional responses to pathways: roles in the causes and treatment of cancer Intra-cel…
  • Some Example Projects: Regulation of HDM2 and HDMX proteins The HDM2 oncoprotein is the majo…
  • Role of CtBP transcriptional repressors in cancer cell proliferation and survival In common …
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Professor Jeremy Frey

Professor of Physical Chemistry

Accepting applications from PhD students

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Professor Jeremy Webb

Professor of Microbiology

Research interests

  • Microbial biofilms and their control
  • Adaptive biology and evolution of microorganisms
  • Biofilm-associated infection

Accepting applications from PhD students

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Miss Jessica Boxall ANutr

Research Fellow

Research interests

  • Public Health
  • Nutrition
  • Food Security
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Dr Jessica Nelson PhD

Lecturer in Advanced Cell Models

Research interests

  • Cancer stem cell biology
  • Tissue Repair Mechanisms
  • Pancreatic cancer progression

Accepting applications from PhD students

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Professor Jessica Teeling

Prof of Experimental Neuroimmunology

Research interests

  • Neuroimmunology
  • Systemic inflammation
  • Antibody-mediated immunotherapy

Accepting applications from PhD students

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Professor Jim Anderson BA, PhD, PFHEA

Professor of Mathematics

Research interests

  • Hyperbolic space and its isometries
  • Kleinian groups (discrete groups of isometries of hyperbolic 3-space)
  • Signatures of actions of automorphism groups on Riemann surfaces

Accepting applications from PhD students

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Professor Jo Slater-Jefferies PhD, MBA, CMgr, MCMI

CEO-National Biofilms Innovation Centre
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Professor Joanne Turney

Professor of Fashion and Textiles

Accepting applications from PhD students

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Related research institutes, centres and groups

Related research institutes, centres and groups

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We welcome new members. To join, or find out more about FortisNet or MyAge, please email the Institute for Life Sciences team.