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The University of Southampton

Dr Mark Lown BEng, PhD, MBBS, MRCGP

Clinical Lecturer

Dr Mark Lown's photo

Dr Mark Lown is a Clinical Lecturer within Medicine at the University of Southampton and a GP at Highfield Health in Southampton.

Dr Lown, recently held an NIHR in-practice fellowship at Southampton and has current interests in nutrition and cardiovascular medicine research in primary care. Being dual qualified as both an Engineer and GP, he also has a special interest in medical technology.

Dr Lown recently completed a positive trial investigating the effects of a plant extract (Mulberry) to reduce glucose and insulin rises following ingestion of carbohydrate. Current trials include a large multi-centre trial investigating probiotics to reduce infection rates and antibiotic resistance in care home residents (PRINCESS), a trial investigating blood pressure medication reduction in the elderly (OPTIMISE), an AF screening trial using consumer devices (SAFETY) and a retrospective cohort study evaluating the long-term effects of lengthy antibiotics.

Research group

Primary Care, Population Sciences and Medical Education

Affiliate research group

Primary Care Research group

Research project(s)

OPTIMISE - OPtimising Treatment for MIld Systolic hypertension in the Elderly

The population is getting older (over 3 million people [5%] in the UK are >80 years) and the number of people living with multiple long-term conditions taking multiple drugs is increasing. High blood pressure is one of the most common conditions in older patients and up to half of this population receive two or more drugs to treat it. However, recent evidence suggests that large reductions in blood pressure, and too many drug prescriptions may be associated with an increase in serious falls and death in the elderly.  

PRINCESS - Probiotics to reduce infections in care home residents, the PRINCESS trial

PROBITY - Prolonged Antibiotic Use, Inflammation and Obesity - a retrospective cohort study

This is a retrospective cohort study to investigate the long-term effects of prolonged antibiotic consumption on health.

SAFETY - Screening for Atrial Fibrillation using Economical and accurate TechnologY - a pilot study

This is a case-control study to investigate the accuracy of inexpensive commercial heart-rate/rhythm monitoring devices to detect Atrial Fibrillation (AF) in conjunction with a novel algorithm based on digital entropy.

GP at Highfield Health, Southampton

PhD supervisor

Supervisor of medical BMedSci students

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  • PhD student Doug Hardman
  • 4th year medical student projects
Dr Mark Lown
Primary Care and Population Sciences
Faculty of Medicine
University of Southampton
Aldermoor Health Centre
Aldermoor Close
SO16 5ST


Room Number: 9590 AHC/115/S2

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