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Dr Simon DS Fraser

Associate Professor of Public Health

As a public health doctor building on my past experience as a GP, my research focuses on chronic disease and its impact at population level. I am passionate about research that will help to improve health care, reduce inequalities and improve outcomes for the growing numbers of people living with long term conditions. My work focuses on kidney disease and its comorbidities.

The greatest burden of long term conditions like chronic kidney disease falls on those with the least resources, and multimorbidity is becoming the norm…

Simon Fraser is Associate Professor of Public Health in Primary Care and Population Sciences. He qualified in medicine from Southampton in 1992 and trained as a GP on the Winchester VTS scheme. After ten years as a full time Principal in General Practice in Southampton, he joined the Wessex Public Health training programme while continuing as a part time GP. He became interested in Academic Public Health and completed his doctoral degree in 2014 on the epidemiology of chronic kidney disease, with a particular interest in inequalities and health literacy.

Qualifications

Academic

BM, University of Southampton 1992

MSc Public Health, London School of Hygiene and Tropical Medicine 2009

DM, University of Southampton 2014

Professional

DRCOG 1994

DCH 1995

MRCGP 1998

Dip Pall Med 2002

FHEA 2016

MFPH 2011

FFPH 2017

Research

Responsibilities

Publications

Teaching

Contact

Research interests

Simon is currently researching the impact of comorbidities in people with chronic kidney disease and methods of improving prevention of acute kidney injury.

His interests include the use of routine data for research. He is currently using the Hampshire Health Record, an anonymised, linked database of over a million people, to investigate chronic kidney disease and acute kidney injury.

PhD research

Inequalities, outcomes, and health literacy in people with chronic kidney disease

Supervisor: Prof Paul Roderick

Research group

Primary Care & Population Sciences

Affiliate research group

Population Health Sciences Research group

Research project(s)

HHRCKD Hampshire Health Record Chronic Kidney Disease study

The Hampshire Acute Kidney Injury Study

Simon is co-organiser of the Primary Care and Population Science seminar programme.

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Articles

Sawhney, S., Robinson, H. A., van der Veer, S., Hounkpatin, H., Scale, T., Chess, J., ... Fraser, S. (2018). Acute kidney injury in the UK: A replication cohort study of the variation across three regional populations. BMJ Open, BMJ Open 2018;8:e019435; doi:10.1136/ bmjopen-2017-019435. DOI: 10.1136/bmjopen-2017-019435
Steenkamp, R., Pyart, R., & Fraser, S. (2018). UK renal registry 20th annual report: Chapter 5 survival and cause of death in UK adult patients on renal replacement therapy in 2016: National and centre-specific analyses. Nephron, 139, 117-150. DOI: 10.1159/000490963
on behalf of ATTOM investigators (2017). A systematic review of the prevalence and associations of limited health literacy in CKD. Clinical Journal of the American Society of Nephrology, 12(7), 1070-1084. [CJN.12921216]. DOI: 10.2215/CJN.12921216
Sawhney, S., & Fraser, S. (2017). Epidemiology of AKI: Utilizing large databases to determine the burden of AKI. Advances in Chronic Kidney Disease, 24(4), 194-204. DOI: 10.1053/j.ackd.2017.05.001
on behalf of the ATTOM investigators (2017). Health literacy and patient outcomes in chronic kidney disease: a systematic review. Nephrology, Dialysis, Transplantation. DOI: 10.1093/ndt/gfx293
Stel, V. S., Bruck, K., Fraser, S., Zoccali, C., Massy, Z. A., & Jager, K. J. (2017). International differences in chronic kidney disease prevalence: a key public health and epidemiologic research issue. Nephrology, Dialysis, Transplantation, 1-18. DOI: 10.1093/ndt/gfw420
Teasdale, E., Leydon, G., Fraser, S., Roderick, P., Taal, M., & Tonkin-Crine, S. (2017). Patients' experiences after CKD diagnosis: a meta-ethnographic study and systematic review. American Journal of Kidney Diseases, 70(5), 656-665. DOI: 10.1053/j.ajkd.2017.05.019
Jager, K. J., & Fraser, S. D. S. (2017). The ascending rank of CKD in the global burden of disease study. Nephrology, Dialysis, Transplantation, 1-53. DOI: 10.1093/ndt/gfw330
Fraser, S., Fenton, A., Harris, S., Shardlow, A., Liabeuf, S., Massy, Z., ... Taal, M. W. (2017). The association of serum free light chains with mortality and progression to end-stage renal disease in chronic kidney disease: systematic review and individual patient data meta-analysis. Mayo Clinic Proceedings, 92(11), 1671-1681. DOI: 10.1016/j.mayocp.2017.08.021
Shardlow, A., McIntyre, N., Fraser, S., Roderick, P., Raftery, J., Fluck, R. J., ... Taal, M. (2017). The clinical utility and cost impact of Cystatin C measurement in the diagnosis and management of chronic kidney disease: a primary care cohort study. PLoS Medicine, 14(10). DOI: 10.1371/journal.pmed.1002400
Methven, S., Steenkamp, R., & Fraser, S. (2017). UK Renal Registry 19th Annual Report: Chapter 5 Survival and Causes of Death in UK Adult Patients on Renal Replacement Therapy in 2015: National and Centre-specific Analyses. Nephron Clinical Practice, 137, 117-150. DOI: 10.1159/000481367
Johnson, M., Hounkpatin, H., Fraser, S., Culliford, D., Uniacke, M., & Roderick, P. (2017). Using a linked database for epidemiology across the primary and secondary care divide: acute kidney injury. BMC Medical Informatics and Decision Making, 17(106). DOI: 10.1186/s12911-017-0503-8
Iwagami, M., Tomlinson, L., Mansfield, K., Casula, A., Caskey, F., Aitken, G., ... Nitsch, D. (2017). Validity of estimated prevalence of decreased kidney function and renal replacement therapy from primary care electronic health records compared to national survey and registry data in the UK. Nephrology, Dialysis, Transplantation, 1-35. DOI: 10.1093/ndt/gfw318
Fraser, S. D. S., & Blakeman, T. (2016). Chronic kidney disease: identification and management in primary care. Pragmatic and Observational Research, 2016:7, 21-32. DOI: 10.2147/POR.S97310
Fraser, S. (2016). How can we prevent type 2 diabetes in children? The Conversation, 1.
Sawhney, S., Fluck, N., Fraser, S. D., Marks, A., Prescott, G. J., Roderick, P. J., & Black, C. (2016). KDIGO-based acute kidney injury criteria operate differently in hospitals and the community—findings from a large population cohort. Nephrology, Dialysis, Transplantation, 31(6), 922-929. DOI: 10.1093/ndt/gfw052
Fraser, S., & Taal, M. (2016). Multimorbidity in people with CKD: implications for outcomes and treatment. Current Opinion in Nephrology & Hypertension, 1-19. DOI: 10.1097/MNH.0000000000000270
Fraser, S. D. S., Roderick, P. J., & Taal, M. W. (2016). Where now for proteinuria testing in chronic kidney disease? Good evidence can clarify a potentially confusing message. British Journal of General Practice, 66(645), 215-217. DOI: 10.3399/bjgp16X684721
Fraser, S. D. S., Aitken, G., Taal, M. W., Mindell, J. S., Moon, G., Day, J., ... Roderick, P. J. (2015). Exploration of chronic kidney disease prevalence estimates using new measures of kidney function in the health survey for England. PLoS ONE, 10(2), e0118676. DOI: 10.1371/journal.pone.0118676
Fraser, S. D. S., & George, S. (2015). Perspectives on differing health outcomes by city: accounting for Glasgow's excess mortality. Risk Management and Healthcare Policy, 2015(8), 99-110. DOI: 10.2147/RMHP.S68925
Nunn, R., Jawad, M., Cruickshank, H., Poole, R., Vass, C., & Fraser, S. (2015). Perspectives on Ebola screening at ports of entry in the UK. Perspectives in Public Health, 135(2), 66-67. DOI: 10.1177/1757913915570778
Assi, L. K., McIntyre, N., Fraser, S. D. S., Harris, S., Hutchison, C., McIntyre, C. W., ... Taal, M. W. (2015). The association between polyclonal combined serum free light chain concentration and mortality in individuals with early chronic kidney disease. PLoS ONE, 10(7), 1-15. DOI: 10.1371/journal.pone.0129980
Fraser, S. D. S., Roderick, P. J., May, C. R., McIntyre, N., McIntyre, C., Fluck, R. J., ... Taal, M. W. (2015). The burden of comorbidity in people with chronic kidney disease stage 3: a cohort study. BMC Nephrology, 16, 1-11. DOI: 10.1186/s12882-015-0189-z
Fraser, S. D. S., Parkes, J., Culliford, D., Santer, M., & Roderick, P. J. (2015). Timeliness in chronic kidney disease and albuminuria identification: a retrospective cohort study. BMC Family Practice, 16(1). DOI: 10.1186/s12875-015-0235-8
Moon, G., Aitken, G., Roderick, P., Fraser, S., & Rowlands, G. (2015). Towards an understanding of the relationship of functional literacy and numeracy to geographical health inequalities. Social Science & Medicine, 143, 185-193. DOI: 10.1016/j.socscimed.2015.08.045
Bruck, K., Stel, V. S., Fraser, S. D. S., De Goeij, M. C. M., Caskey, F., Abu-Hanna, A., & Jager, K. J. (2015). Translational research in nephrology: chronic kidney disease prevention and public health. Clinical Kidney Journal, 1-9. DOI: 10.1093/ckj/sfv082
Fraser, S. D., Roderick, P. J., McIntyre, N. J., Harris, S., McIntyre, C., Fluck, R., & Taal, M. W. (2014). Assessment of proteinuria in patients with chronic kidney disease stage 3: albuminuria and non-albumin proteinuria. PLoS ONE, 9(5), e98261. DOI: 10.1371/journal.pone.0098261
Aitken, G. R., Roderick, P. J., Fraser, S. D. S., Mindell, J. S., O'Donoghue, D., Day, J., & Moon, G. (2014). Change in prevalence of chronic kidney disease in England over time: comparison of nationally representative cross-sectional surveys from 2003 to 2010. BMJ Open, 4(9), 1-13. DOI: 10.1136/bmjopen-2014-005480
Lehman, C., Philips, D., Crowe, S., Lemon, D., & Fraser, S. (2014). Letter. Discrepancies between data on various PHE websites. British Medical Journal, 349(g7080), 1-1. DOI: 10.1136/bmj.g7080
Fraser, S. D. S., Roderick, P. J., McIntyre, N. J., Harris, S., McIntyre, C. W., Fluck, R. J., & Taal, M. W. (2014). Skin autofluorescence and all-cause mortality in Stage 3 CKD. Clinical Journal of the American Society of Nephrology, 9. DOI: 10.2215/CJN.09510913
Fraser, S. D. S., Roderick, P. J., Aitken, G., Roth, M., Mindell, J. S., Moon, G., & O'Donoghue, D. (2013). Chronic kidney disease, albuminuria and socioeconomic status in the Health Surveys for England 2009 and 2010. Journal of Public Health, 1-10. DOI: 10.1093/pubmed/fdt117
Gamblin, J., Jefferies, J. M. C., Harris, S., Ahmad, N., Marsh, P., Faust, S. N., ... Clarke, S. C. (2013). Nasal self-swabbing for estimating the prevalence of Staphylococcus aureus in the community. Journal of Medical Microbiology, 62(Pt 3), 437-440. DOI: 10.1099/jmm.0.051854-0
Fraser, S. D. S., Roderick, P. J., Casey, M., Taal, M. W., Yuen, H. M., & Nutbeam, D. (2013). Prevalence and associations of limited health literacy in chronic kidney disease: a systematic review. Nephrology, Dialysis, Transplantation, 28(1), 129-137. DOI: 10.1093/ndt/gfs371
Fraser, S. D., Roderick, P. J., McIntyre, N. J., Harris, S., McIntyre, C. W., Fluck, R. J., & Taal, M. W. (2013). Suboptimal blood pressure control in chronic kidney disease stage 3: baseline data from a cohort study in primary care. BMC Family Practice, 14, 88. DOI: 10.1186/1471-2296-14-88
Fraser, S. D. S., Roderick, P. J., McIntyre, N. J., Harris, S., McIntyre, C. W., Fluck, R. J., & Taal, M. W. (2012). Socio-economic disparities in the distribution of cardiovascular risk in chronic kidney disease stage 3. Nephron Clinical Practice, 122(1-2), 58-65. DOI: 10.1159/000348835
Anstee, S., Price, A., Young, A., Barnard, K., Coates, B., Fraser, S., & Moran, R. (2011). Developing a matrix to identify and prioritise research recommendations in HIV prevention. BMC Public Health, 11(381), 1-8. DOI: 10.1186/1471-2458-11-381
Fraser, S. D. S., Watkinson, G. E., Rennie, C. A., King, D., Sanderson, H., Edwards, L., & Roderick, P. (2011). Sociodemographic differences in diabetic retinopathy screening; using patient-level primary care data for health equity audit. Clinical Audit, 3, 7-15. DOI: 10.2147/CA.S25313
Fraser, S., & Lock, K. (2010). Cycling for transport and public health: a systematic review of the effect of the environment on cycling. European Journal of Public Health, 21(6), 738-743. DOI: 10.1093/eurpub/ckq145
Fraser, S. (2010). The Wizard, the Gatekeeper and the Watchman - a fairy tale of resources and decisions. British Journal of General Practice, 60(576), 544-545. DOI: 10.3399/bjgp10X514972
Fraser, S., & Ayres, C. (2009). The doctor's casebook - a process of discovery. Scottish Medical Journal, 54(3), 36-41. DOI: 10.1258/rsmsmj.54.3.36
Fraser, S. (2005). Six months in public health: reflections on a GP bursary scheme. Education for Primary Care, 16(2), 203-205.

Reports

Fraser, S. (2016). On the level. Evidence for action on type 2 diabetes. (NIHR Themed Review). National Institute for HealthResearch.
Steenkamp, R., Rao, A., & Fraser, S. (Ed.) (2015). UK Renal Registry 18th Annual Report (December 2015) Chapter 5: Survival and causes of death in UK adult patients on renal replacement therapy in 2014: national and centre-specific analysis. Bristol, GB: UK Renal Registry.

Thesis

Fraser, S. D. S. (2014). Inequalities, outcomes, and health literacy in people with chronic kidney disease

Simon is module lead for the Health Services Organisation and Evaluation module of the MSc Public Health.

He is also Public Health and Evidence Based Medicine lead for the BM4 programme.

Dr Simon DS Fraser
Level C, South Academic Block Room number AC22 Mailpoint 805 Primary Care and Population Sciences Southampton General Hospital Tremona Road Southampton SO16 6YD

Tel: 02381 206530

Email: s.fraser@soton.ac.uk

Room Number: SGH/AC23/MP805

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