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Research group

Interdisciplinary Musculoskeletal Health

4 Stained femur cross sections

The University hosts a substantial interdisciplinary community of researchers working to transform musculoskeletal health across the life course.

About

With expertise in regenerative medicine, physiology, engineering, orthopaedics, prosthetics and orthotics, rehabilitation and assistive technologies, epidemiology and clinical trial design, we aim to improve lives by delivering improved treatments, increasing the speed to market of musculoskeletal-focused technology and training the next generation of scientists and engineers. 

The population across the globe is living longer, which brings a number of healthcare challenges, especially in musculoskeletal health. The burden of age-related disease and injury is rising rapidly, having a detrimental impact on people’s quality of life and increasing the costs of healthcare provision. Loss of muscle mass and function is the leading reason for loss of independence in later life, and causes impaired mobility, falls, fractures, physical disability, increased insulin resistance and associated co-morbidities, and mortality. The number of hip fractures is expected to rise to 6.3 million by 2050 and the number of diabetic lower limb amputations has now risen to 7,000 per year in the UK and over 70,000 in the USA. 

The University is working to meet these challenges by creating networks of experts working in interdisciplinary musculoskeletal health research to develop new technologies, interventions and practices that will have a positive effect on people’s lives:

  • FortisNet is an interdisciplinary research network of clinical, academic and industrial partners that aims to develop products and services to transform musculoskeletal health. Launched in 2016, we have fostered over 50 new collaborations with other universities from across the UK, the NHS and industry. We have developed courses with national partners to help innovators understand how to bring medical technologies to market, and through investment in interdisciplinary studentships we are working to dissolve discipline boundaries, to train a new generation of life scientists and engineers for the benefit of society.
  • MyAge (Muscle resilience across the life course: from cells to society) is one of eleven UK Ageing Networks, funded by the Biotechnology and Biological Sciences Research Council and Medical Research Council. Led by the Institute for Life Sciences, together with partners from Birmingham, Nottingham and Imperial, the network will guide the future of muscle resilience research through roadmap development and interdisciplinary collaboration.

Research highlights

Preventing the transmission of non-communicable disease risk between generations

Research from the Developmental Origins of Health and Disease Centre demonstrates how the diet and lifestyle choices of prospective parents and pregnant mothers can affect the long-term health of their children.

Using nanoclay gel to regrow, repair and replace damaged cells

Southampton researchers have developed an innovative medical clay that can be used to apply regenerative medicine to patients with musculoskeletal conditions.

People, projects and publications

People

Dr Owen Rackham MSc, PhD

Associate Professor

Accepting applications from PhD students

Email: o.j.l.rackham@soton.ac.uk

Address: B85, East Highfield Campus, University Road, SO17 1BJ

Professor Pete Worsley

Professor

Research interests

  • Skin and Soft Tissue Health
  • Bioengineering
  • Healthcare Technologies

Accepting applications from PhD students

Email: p.r.worsley@soton.ac.uk

Address: Southampton General Hospital, Tremona Road Shirley, SO16 6YD

Professor Peter Smith BSc, PhD, MA, FRSB

Professor of Life Sciences

Email: p.j.smith@soton.ac.uk

Address: B85, East Highfield Campus, University Road, SO17 1BJ

Dr Rahul Tare

Lecturer

Research interests

  • Human stem cells
  • Skeletal development
  • Tissue engineering primarily, cartilage tissue engineering

Accepting applications from PhD students

Email: r.tare@soton.ac.uk

Address: Southampton General Hospital, Tremona Road Shirley, SO16 6YD

Dr Richard Cook

Associate Professor

Research interests

  • Mechanical and tribological testing of hydrogels for orthopaedic and tissue engineering
  • The tribology of tooth brushing.
  • Efficacy testing of products for dental hypersensitivity management.

Email: r.b.cook@soton.ac.uk

Address: B15, East Highfield Campus, University Road, SO17 1BJ

Dr Ruth Turk

Associate Professor

Email: r.turk@soton.ac.uk

Address: B67, West Highfield Campus, University Road, SO17 1BJ

Professor Sonia Zakrzewski

Prof of Bioarchaeology & BioAnthropology

Research interests

  • bioarchaeology and palaeopathology
  • disAbility, impairment, injury and disease
  • race, migration and mobility

Accepting applications from PhD students

Email: s.r.zakrzewski@soton.ac.uk

Address: B65, Avenue Campus, Highfield Road, SO17 1BF

Professor Sumeet Mahajan MSc, MTech, PhD, FHEA, FRSC

Prof of Molecular BioPhotonics & Imaging

Research interests

  • New chemical biology methods based on Raman spectroscopy and label-free imaging
  • Methodology and device development for commercialisation and clinical translation
  • Neuro-diagnostics and early detection of dementia and neurodegenerative diseases

Accepting applications from PhD students

Email: s.mahajan@soton.ac.uk

Address: B85, East Highfield Campus, University Road, SO17 1BJ

Professor Xunli Zhang PhD, DIC, FRSC, CChem, CEng

Head of Department-Chemical Engineerg

Research interests

  • Xunli’s key expertise lies in the area of microfluidics technology from design and fabrication of microfluidic devices, through the development of in-situ monitoring methods for bio/chemical processes, to microfluidic modelling, microsystems integration and automation. The application is largely associated with biomedical challenges like patient specific design of microfluidic devices for cancer treatment, rapid diagnosis, and tackling antimicrobial resistance (AMR). The continuous flow reactors have been used for the synthesis of a range of nanoparticles, both organic and inorganic, for application in drug delivery and energy saving. The technologies developed in his research have also found great potential for industrial applications through a variety of industrial collaborations. 

Accepting applications from PhD students

Email: xl.zhang@soton.ac.uk

Address: B7, East Highfield Campus, University Road, SO17 1BJ

Related research institutes, centres and groups

Related research institutes, centres and groups

Connect with us

We welcome new members. To join, or find out more about FortisNet or MyAge, please email the Institute for Life Sciences team.
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