About
Ivo Tews uses crystallography to study molecular interactions. Particular intrests are in large dynamic macromolecular complexes and time resolved techniques. As a member of the CCP4 project for crystallographic software he chairs working group 2, and is engaged in Synchrotron Science at the Diamond Light Source and the EUropean Synchtrotron Radiation Facilty.
Research
Research groups
Research interests
- Natural products biosynthesis: a complex cascade of catalytic steps in vitamin B6 biosynthesis is characterised by structures or reaction intermediates in the large PLP syntase complexEdit
- Bacterial biofilms: understanding of RedOx regulated phosphodiesterase activity in dispersal of biofilms to address chronic infections
- Cancer immunology: together with Cancer Immunology at Southampton we use a structure based apporach in developing novel cancer therapie
Research projects
Active projects
Researchers:
Researchers:
Sponsor: Science And Technology Facilities Council
Sponsor: Medical Research Council
Researchers:
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Sponsor: Cancer Research UK
Researchers:
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Sponsor: EPSRC
Completed projects
Researchers:
Researchers:
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Researchers:
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Sponsor: Cancer Research UK
Researchers:
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Sponsor: Wessex Medical Research
Publications
61 publications
Page 4 of 7
Curtis William Phippen,
Halina Mikolajek,
Henry George Schlaefli,
& Ivo Tews
, 2014
, FEBS Letters
, 588 (24) , 4631--4636
Type: article
Joanna Tripp,
Alexander Hahn,
Patrick Koenig,
Nadine Flinner,
Daniela Bublak,
Eva M. Brouwer,
Franziska Ertel,
Oliver Mirus,
Irmgard Sinning,
Ivo Tews,
& Enrico Schleiff
, 2012
, The Journal of Biological Chemistry
, 287 (29) , 24164--24173
Type: article
Gabriela Guedez,
Katharina Hipp,
Volker Windeisen,
Bianca Derrer,
Martin Gengenbacher,
Bettina Boettcher,
Irmgard Sinning,
Barbara Kappes,
& Ivo Tews
, 2012
, Structure
, 20 (1) , 172--184
Type: article
Domenico Lupo,
Christine Vollmer,
Markus Deckers,
David U Mick,
Ivo Tews,
Irmgard Sinning,
& Peter Rehling
, 2011
, Traffic
, 12 (10) , 1457--1466
Type: article
Tathagata Mukherjee,
Jeremiah Hanes,
Ivo Tews,
Steven E. Ealick,
& Tadhg P. Begley
, 2011
, Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics
, 1814 (11) , 1585--1596
Type: article
Barbara Kappes,
Ivo Tews,
Alexandra Binter,
& Peter Macheroux
, 2011
, Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics
, 1814 (11) , 1567--1576
Type: article
Mislav Oreb,
Anja Höfle,
Patrick Koenig,
Maik S. Sommer,
Irmgard Sinning,
Fei Wang,
Ivo Tews,
Danny J. Schnell,
& Enrico Schleiff
, 2011
, Biochemical Journal
, 436 (2) , 313--319
DOI: 10.1042/BJ20110246
Type: article
Bianca Derrer,
Volker Windeisen,
Gabriela Guédez Rodríguez,
Joerg Seidler,
Martin Gengenbacher,
Wolf D Lehmann,
Karsten Rippe,
Irmgard Sinning,
Ivo Tews,
& Barbara Kappes
, 2010
, FEBS Letters
, 584 (19) , 4169--4174
Type: article
Patrick Koenig,
Oliver Mirus,
Raimund Haarmann,
Maik S. Sommer,
Irmgard Sinning,
Enrico Schleiff,
& Ivo Tews
, 2010
, The Journal of Biological Chemistry
, 285 (23) , 18016--18024
Type: article
Silvia Wallner,
Martina Neuwirth,
Karlheinz Flicker,
Ivo Tews,
& Peter Macheroux
, 2009
, Biochemistry
, 48 (9) , 1928--1935
DOI: 10.1021/bi801887r
Type: article
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Biography
Prizes
- David Blow Prize (2011)
- PD, venia legendi (2011)