Aims and Objectives
Having successfully completed this module you will be able to:
- Describe nucleophilic substitution reactions by both the SN1 and SN2 mechanisms
- Present the results of a practical investigation in a concise manner.
- Apply the curly arrow notation to describe both resonance and reaction mechanisms
- Describe the structure (including electronic configuration) of organic molecules in terms of orbitals, hybridisation and conformation, including stereoisomerism
- Predict the relative acidity and basicity of organic molecules, and describe these properties with the concepts of pKa and pKaH
- Explain the factors that influence SN1 and SN2 reaction rates, including the roles of steric effects, orbital effects and electronic effects.
- Understand and use sawhorse and Newman projections, 3D structures of organic molecules including cyclic structures
- Explain the connections between electronic effects and acidity/basicity
- Recognise and name a wide range of functional groups and interpret their IR spectra
- Explain the concept of aromaticity and identify both aromatic and non-aromatic molecules
- Set up glassware and apparatus to conduct experiments in Organic Chemistry.
- Understand the relative stability of conformations of linear and cyclic organic molecules.
- Draw representations of the chemical structure of organic molecules using a concise notation.
- Interpret data from a range of physical techniques to characterise Organic compounds.
- Name a wide range of organic molecules, including stereochemistry
- Identify electron-rich and electron-poor sites within molecules, by using the concepts of electronegativity, inductive effects and mesomeric (resonance) effects
- Evaluate the risks associated with an experiment and understand how to mitigate those risks.
Structure – of molecules: functional groups, isomerism including optical activity, nomenclature, introduction to infrared spectroscopy (functional groups); bonding (orbitals, hybridisation and shape of organic species); conformational analysis.
Reactivity – curly arrows, electron-rich and electron-deficient species, acidity (alcohols, phenols, carboxylic acids, and C—H acids); basicity (BuLi, LDA, hydroxide and alkoxides, amines); resonance; aromaticity and introduction of the reactivity of aromatic compounds compared to alkenes; nucleophilic substitution at sp³ carbon (SN1 and SN2 mechanisms).
Completion of four practical experiments and associated reports covering a range of topics and skills in organic chemistry including the application of a variety of fundamental techniques and methodologies (including spectroscopy) to the synthesis and analysis of molecules and materials; the ability to analyse experimental data to provide an explanation for the observed experimental outcomes; understanding the importance of experimental safety and time management.
Learning and Teaching
Teaching and learning methods
Lectures, tutorials with group working and tutor support
Practical chemistry: Prelaboratory e-learning; pre-lab skills lectures/ Seminars; practical sessions, supporting demonstrations, group and one-to-one tuition.
|Wider reading or practice||15|
|Preparation for scheduled sessions||48|
|Total study time||150|
Resources & Reading list
James Keeler and Peter Wothers (2008). Chemical Stucture and Reactivity. OUP.
J Clayden, N Greeves and S Warren (2012). Organic Chemistry. Oxford: OUP.
Andrew Burrows, John Holman, Andrew Parsons, Gwen Pilling, and Gareth Price (2009). Chemistry3: Introducing inorganic, organic, and physical chemistry. OUP.
All absences from practical sessions must be validated and unexcused absences will result in failure of the module.
Repeat year externally: allowed if practical attendance criteria has been met. The practical marks are retained, the theory assessment is exam only.
Repeat year internally: note that practical may be reassessed by resubmission of reports or repeated.
This is how we’ll give you feedback as you are learning. It is not a formal test or exam.In-class Test
This is how we’ll formally assess what you have learned in this module.
This is how we’ll assess you if you don’t meet the criteria to pass this module.
Repeat type: Internal & External